Comparing KanKen 1.25 mg and Danazol 80 mg for Blood Pressure Management - Cardiology

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Kankun 1.25 mg and De-An-Wen 80 mg?


Hello, Doctor.
I previously had high blood pressure, but now that my lifestyle has become more regular, it has decreased.
Could you please tell me which medication has a milder effect: Concor 1.25 mg or Diltiazem 80 mg (which is half of 160 mg)? My current blood pressure is 104/61 and my heart rate is 58.
Do I still need to take medication? I'm concerned that taking it might lower my blood pressure too much.

Niming, 40~49 year old female. Ask Date: 2021/09/09

Dr. He Dongjin reply Cardiology


Hello, if your heart rate stabilizes at 80, you may consider stopping the medication completely.
Changhua Hospital cares about you.

Reply Date: 2021/09/09

More Info


When comparing KanKen (Carvedilol) 1.25 mg and Danazol 80 mg for blood pressure management, it's important to understand the pharmacological properties and intended uses of these medications. KanKen is a non-selective beta-blocker that is primarily used to manage hypertension and heart failure. It works by blocking beta-adrenergic receptors, leading to a decrease in heart rate and cardiac output, which ultimately lowers blood pressure. On the other hand, Danazol is primarily used for conditions like endometriosis and fibrocystic breast disease, and it has androgenic properties that can influence blood pressure but is not primarily indicated for hypertension management.

In your case, with a blood pressure reading of 104/61 mmHg and a heart rate of 58 beats per minute, it appears that your blood pressure is on the lower end of the normal range. Given this situation, it is understandable that you are concerned about the potential for your blood pressure to drop further if you continue taking antihypertensive medications.
If you have been experiencing a significant improvement in your blood pressure due to lifestyle changes, such as better diet, regular exercise, and stress management, it may be appropriate to reassess your medication regimen. The goal of hypertension treatment is to achieve optimal blood pressure control while minimizing side effects and the risk of hypotension (abnormally low blood pressure).
In general, if your blood pressure consistently remains low, it may be advisable to reduce or even discontinue the use of KanKen, especially if you are experiencing symptoms such as dizziness or fatigue. However, any changes to your medication should be made in consultation with your healthcare provider. They can evaluate your overall health, consider any other medications you may be taking, and determine the best course of action based on your specific circumstances.

It is also worth noting that the effects of beta-blockers like KanKen can vary from person to person. Some individuals may tolerate lower doses well, while others may experience side effects even at standard doses. Therefore, close monitoring of your blood pressure and heart rate is essential, especially when making adjustments to your medication.

In summary, while KanKen is more effective for blood pressure management compared to Danazol, your current low blood pressure readings suggest that you may not need to continue taking it at this time. Always consult with your healthcare provider before making any changes to your medication regimen to ensure that you are making safe and informed decisions regarding your health.

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