Hepatitis B Transmission: Myths and Facts - Gastroenterology and Hepatology

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Concerns about Hepatitis B transmission?


Hello doctor! I have a friend who says he is a carrier of hepatitis B and that he was infected perinatally.
However, he claims that he will not transmit the virus to others.
Is there any truth to this statement, or am I misunderstanding something?

A Nan, 20~29 year old female. Ask Date: 2021/09/13

Dr. Chen Shidian reply Gastroenterology and Hepatology


Blood can still transmit infections (hence, blood donation is not allowed), while food does not transmit infections.

Reply Date: 2021/09/13

More Info


Hepatitis B is a viral infection that primarily affects the liver and can lead to chronic liver disease, cirrhosis, and liver cancer. Understanding its transmission is crucial for prevention and management. Your friend's assertion that he cannot transmit the virus to others is a common misconception that needs clarification.

Firstly, Hepatitis B is transmitted through contact with infectious body fluids, including blood, semen, and vaginal secretions. The most common routes of transmission include:
1. Vertical Transmission: This occurs when an infected mother passes the virus to her baby during childbirth. This is a significant route of transmission, especially in regions where Hepatitis B is endemic.

2. Horizontal Transmission: This includes sharing needles, unprotected sexual contact, and exposure to infected blood through cuts or abrasions. Activities such as sharing razors, toothbrushes, or any personal items that may have come into contact with blood can also pose a risk.

3. Occupational Exposure: Healthcare workers are at risk if they come into contact with infected blood or bodily fluids.

Now, regarding your friend's claim, it is important to note that while some individuals with chronic Hepatitis B may have low viral loads or undetectable levels of the virus, they can still potentially transmit the virus to others. The presence of Hepatitis B surface antigen (HBsAg) in the blood indicates an active infection, and these individuals can be infectious, regardless of their viral load.
Furthermore, the presence of Hepatitis B e-antigen (HBeAg) is often associated with high levels of viral replication, indicating a higher risk of transmission. Conversely, the presence of Hepatitis B e-antibody (Anti-HBe) typically suggests a lower level of viral replication and a reduced risk of transmission, but it does not eliminate the possibility entirely.

It's also important to understand that individuals who are Hepatitis B carriers may not exhibit symptoms or have normal liver function tests, which can lead to a false sense of security regarding their infectivity. Regular monitoring of liver function and viral load is essential for managing the health of individuals with chronic Hepatitis B.

In terms of prevention, vaccination against Hepatitis B is highly effective. The vaccine can prevent infection in individuals who have not been exposed to the virus. For those who are already infected, antiviral treatments are available to manage the infection and reduce the risk of transmission.

In summary, while your friend may believe he cannot transmit Hepatitis B, it is crucial to understand that chronic carriers can still pose a risk of transmission, especially if they have detectable levels of the virus. Education about the modes of transmission and the importance of safe practices is vital in preventing the spread of Hepatitis B. If your friend is unsure about his status or the implications of being a carrier, it would be advisable for him to consult with a healthcare professional for personalized advice and management.

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