Persistent Throat Discomfort: Seeking Answers for Ongoing Symptoms - Otolaryngology

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Oral and throat issues?


Hello Dr.
Li, I previously mentioned my symptoms on the left side of my oral cavity and throat, including a foreign body sensation and sharp pain in the pharyngeal wall and the base of my left tongue.
There is a slight feeling of inflammation, and in one area, there used to be a white lesion.
Currently, I still experience sharp pain and a foreign body sensation in that location.
The discomfort becomes more pronounced when I turn my neck in certain positions.
I have a persistent feeling of a foreign body from the uvula to the pharyngeal wall, and this has lasted for over five months without any relief.
I had my bilateral tonsils removed six months ago, yet I still feel discomfort on the left side, which is quite bothersome.

I have undergone all necessary examinations at my own expense: a thyroid ultrasound in June showed no abnormalities, an esophagogastroduodenoscopy in July showed no inflammation at the esophageal opening, a nasopharyngoscopy with narrow-band imaging in August showed no significant abnormalities, an MRI of the head and neck with contrast in August also showed no significant findings, and a neck ultrasound in September showed no significant abnormalities.
However, I still have a foreign body sensation and sharp pain from the left side of my mouth (around the occlusion area) to the base of my left tongue and the pharyngeal wall.
I find it difficult to swallow, experiencing a slight sharp pain, and I have been using an anti-inflammatory oral spray.
I would like to ask Dr.
Li if the area I circled in the image can be clearly examined by MRI.
I am considering whether to undergo a whole-body positron emission tomography (PET) scan, but I am concerned about whether this scan can detect any issues in the base of the tongue, oral cavity, or pharyngeal wall.
All of my concerns are related to the left side of my oral cavity and throat, particularly the area behind the uvula and the pharyngeal wall.
When I palpate the pharyngeal wall, it feels hard and protruding, and I am unsure if this is normal (cervical vertebrae).
However, the doctor who performed the endoscopy said there was nothing significant.
Should I undergo a physical examination? Given that I have had so many tests, can we be certain that there are no malignancies? Is it possible that my foreign body sensation is a postoperative complication, or could there be an issue that is not detectable through these tests? I would like to ask Dr.
Li if I should undergo a PET scan.
I am eager for a second opinion.
Thank you.

Miss Yang, 40~49 year old female. Ask Date: 2021/09/18

Dr. Li Jiaxuan reply Otolaryngology


Positron emission tomography (PET) has a higher accuracy, but MRI is also quite accurate; however, every examination has its limitations.
Wishing you safety and health.

Reply Date: 2021/09/18

More Info


Persistent throat discomfort can be a challenging and distressing condition, especially when it lasts for an extended period, as you have described. Your symptoms, including the sensation of a foreign body, pain, and inflammation in the left side of your throat and tongue, warrant careful consideration and evaluation.

From your account, it appears that you have undergone a comprehensive range of diagnostic tests, including thyroid ultrasound, gastroscopy, nasopharyngoscopy, MRI of the head and neck, and neck ultrasound, all of which have returned normal results. This is a positive sign, as it suggests that there are no obvious structural abnormalities or malignancies present in the areas examined. However, the persistence of your symptoms indicates that there may be other factors at play.

One possibility is that you may be experiencing a condition known as globus sensation, which is characterized by the feeling of a lump or foreign body in the throat without any actual obstruction. This condition can be associated with anxiety, stress, or gastroesophageal reflux disease (GERD), even if the esophagus appears normal on examination. It is essential to consider the psychological and physiological aspects of your symptoms, as they can significantly influence your perception of discomfort.

Another potential cause of your symptoms could be related to post-surgical changes. Since you mentioned having had your tonsils removed, it is possible that the surgery has altered the anatomy of your throat, leading to sensations that were not present before. Scar tissue formation or changes in the surrounding tissues could contribute to your ongoing discomfort.

Regarding your question about the effectiveness of MRI in detecting issues in the base of the tongue and throat, while MRI is a valuable imaging tool, it may not always provide the detailed information needed for certain soft tissue structures. A PET scan (positron emission tomography) can be useful in identifying metabolic activity in tissues and may help in cases where there is a suspicion of underlying pathology that is not visible on standard imaging. However, it is essential to discuss the necessity and appropriateness of such a scan with your healthcare provider, as they can guide you based on your specific clinical situation.

In terms of management, it may be beneficial to explore a multidisciplinary approach. Consulting with an otolaryngologist (ENT specialist) who specializes in throat disorders could provide further insights. Additionally, working with a gastroenterologist to evaluate for GERD or other gastrointestinal issues may be worthwhile, as these conditions can contribute to throat discomfort.

Moreover, if anxiety or stress is a contributing factor, engaging in cognitive-behavioral therapy (CBT) or other forms of psychological support may help address the emotional aspects of your symptoms. Relaxation techniques, mindfulness, and stress management strategies can also be beneficial in alleviating discomfort.

In conclusion, while your extensive testing has ruled out many serious conditions, the persistence of your symptoms suggests that further evaluation and a holistic approach may be necessary. It is essential to maintain open communication with your healthcare providers, express your concerns, and collaboratively explore potential next steps in your care. Your comfort and well-being are paramount, and addressing both the physical and emotional components of your symptoms is crucial for achieving relief.

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