Chalazion: Treatment Options and Effectiveness of Doxycycline - Ophthalmology

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A stye has developed into a chalazion?


Hello doctor, I recently developed a stye, and after using eye drops and taking antibiotics for treatment, I noticed a hard lump in the area where the stye was located two weeks later.
It is not visible but can be felt, and I don't usually feel any discomfort.
When I saw the doctor again, he mentioned that the stye had turned into granulation tissue.
I inquired if it could be surgically removed, but the doctor advised against it since there was no pus and prescribed Doxycycline 100mg capsules for me.
However, after taking it for a week, I still feel that the hard lump has not diminished.
I would like to ask: 1.
Is Doxycycline 100mg effective in resolving a chalazion, or is surgical intervention the only option? 2.
Is warm compress effective for a chalazion?

Youzi, 10~19 year old female. Ask Date: 2021/09/22

Dr. Gao Pilin reply Ophthalmology


Hello, Yuzu: 1.
Doxycycline is not used to eliminate chalazia.
It is used to treat infections.
2.
Warm compresses have some effectiveness.
The lump may not resolve quickly and can sometimes persist.
If it continues to be bothersome, please consult a physician to evaluate whether surgical removal is necessary.

Reply Date: 2021/09/22

More Info


Chalazion, commonly referred to as a stye, is a localized swelling on the eyelid caused by the blockage of a meibomian gland. It often follows an episode of a stye or can develop independently. The condition is characterized by a firm, painless lump that may not always be visible but can be felt. In your case, it seems that the initial stye has progressed to a chalazion, which is often composed of granulation tissue.

1. Effectiveness of Doxycycline for Chalazion: Doxycycline is a tetracycline antibiotic that is primarily used to treat bacterial infections. While it is not the first-line treatment for chalazion, it can be prescribed in certain cases, particularly if there is a suspicion of an underlying infection or if the chalazion is associated with blepharitis (inflammation of the eyelid). Doxycycline has anti-inflammatory properties that can help reduce inflammation and promote healing. However, it is important to note that if the chalazion does not respond to doxycycline after a week of treatment, it may not be effective for your specific case. Surgical intervention, such as incision and drainage, is often recommended for persistent chalazia that do not resolve with conservative measures, including antibiotics or warm compresses.

2. Effectiveness of Warm Compresses: Warm compresses are a well-established home remedy for chalazion. The heat helps to soften the hardened oil that is blocking the gland, promoting drainage and reducing inflammation. Applying a warm compress for 10-15 minutes several times a day can be beneficial. It is a non-invasive method that can often lead to resolution of the chalazion without the need for surgical intervention.
In summary, while doxycycline may have some benefits in reducing inflammation associated with chalazion, it is not specifically indicated for its treatment. If the chalazion persists despite antibiotic therapy and warm compresses, surgical removal may be necessary. It is advisable to follow up with your healthcare provider to discuss the best course of action based on your symptoms and response to treatment.
Additionally, if you have any underlying conditions that may contribute to the formation of chalazia, such as seborrheic dermatitis or chronic blepharitis, addressing those conditions may also help prevent future occurrences. Always consult your healthcare provider for personalized medical advice tailored to your specific situation.

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