Positive Fecal Occult Blood: Causes and Concerns - Gastroenterology and Hepatology

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Possible causes of positive fecal occult blood test?


Hello, doctor.
Recently, I started experiencing pain in my lower left abdomen, and I underwent a stool test.
During the stool sample collection, I noticed that the color at the front was particularly dark, and the result came back positive.
I had a colonoscopy two years ago, which only indicated internal hemorrhoids, but my mother, who has no family history, developed stage IV colon cancer within two years in her 50s.
Is there a possibility that I could inherit this? What other reasons could there be for a positive fecal occult blood test? What is the likelihood of a young person developing colon cancer within two years? Are there any successful treatment cases? Can I have a colonoscopy every year? What should I pay attention to? I have already scheduled the examination, but I can't help but worry before seeing the results.
Thank you.

Niming, 20~29 year old female. Ask Date: 2021/10/07

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: A positive test result suggests that you should undergo another colonoscopy.
There are many reasons for a positive fecal occult blood test, including gastric ulcers, enteritis, hemorrhoids, polyps, and cancer.
Any potential source of bleeding could lead to a positive result.
Changhua Hospital cares about your health.
Dr.
Tsai An-Shun.

Reply Date: 2021/10/07

More Info


Understanding positive fecal occult blood (FOBT) results can be concerning, especially when accompanied by symptoms like abdominal pain. The presence of occult blood in the stool can arise from various causes, and it is essential to interpret these results in the context of your overall health and medical history.


Causes of Positive Fecal Occult Blood
1. Hemorrhoids: Given your previous diagnosis of internal hemorrhoids, this could be a benign cause of the positive result. Hemorrhoids can cause bleeding, which may lead to trace amounts of blood in the stool.

2. Gastrointestinal Conditions: Other conditions, such as diverticulosis, peptic ulcers, or inflammatory bowel disease (IBD), can also lead to positive FOBT results. These conditions can cause bleeding in the gastrointestinal tract, which may not always be visible.

3. Polyps or Colorectal Cancer: While your previous colonoscopy showed only hemorrhoids, it is important to note that polyps can develop over time, and some may become cancerous. Family history plays a significant role in colorectal cancer risk, and while your mother's experience raises concerns, it does not guarantee that you will have the same outcome. The risk of developing colorectal cancer increases with age, but younger individuals can also be affected.

4. Dietary Factors: Certain foods, such as red meat, can cause false positives in FOBT. If you consumed a diet high in red meat or certain vegetables (like beets) before the test, this could influence the results.


Risk of Colorectal Cancer in Young Adults
The incidence of colorectal cancer in younger adults has been rising, but it remains relatively low compared to older populations. According to the American Cancer Society, the lifetime risk of developing colorectal cancer is about 4.3% for men and 4.0% for women. However, if you have a family history of colorectal cancer, your risk may be higher, and genetic factors could play a role.


Genetic Considerations
While there is no direct inheritance of colorectal cancer, certain genetic syndromes, such as Lynch syndrome or familial adenomatous polyposis (FAP), can increase the risk. If your family history is concerning, it may be worth discussing genetic counseling with your healthcare provider.


Follow-Up and Screening Recommendations
Given your positive FOBT and family history, it is prudent to follow up with a colonoscopy. Regular screening is essential, especially if you have risk factors. The general recommendation for average-risk individuals is to start screening at age 45, but those with a family history may need to begin earlier.

1. Frequency of Colonoscopies: If your colonoscopy is normal, the typical recommendation is to repeat it every 10 years. However, if you have risk factors or if polyps are found, your doctor may recommend more frequent screenings.

2. Preparation for Colonoscopy: Ensure you follow the preparation instructions carefully. This typically involves dietary restrictions and bowel-cleansing protocols to ensure a clear view during the procedure.


Conclusion
While a positive FOBT can be alarming, it is essential to remember that there are many potential causes, many of which are benign. Your family history does warrant further investigation, but it does not mean you will necessarily face the same fate as your mother. Regular screenings and open communication with your healthcare provider are key to managing your health. If you have any further concerns or symptoms, do not hesitate to reach out to your doctor for guidance.

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