Can Aspirin and Transamin Be Taken Together During Pregnancy? - Obstetrics and Gynecology

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Aspirin and Other Medications During Pregnancy


Hello, doctor.
I am currently almost 16 weeks pregnant and would like to ask if it is safe to take Transamin 250mg/capsule (tranexamic acid) and Bokey 100mg/capsule (enteric-coated aspirin) on the same day.
I am concerned whether there might be any interaction between these two medications that could reduce their effectiveness.
My current pregnancy condition includes slight vaginal bleeding, and my preeclampsia risk values are high.
Thank you.

Lin, 30~39 year old female. Ask Date: 2021/10/10

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, aspirin does not have an effect.
As for hemostatic agents, you can consult the physician who prescribed your medication.
Wishing you good health.

Reply Date: 2021/10/10

More Info


When it comes to taking medications during pregnancy, especially in the context of your question regarding the simultaneous use of Transamin (Tranexamic Acid) and Aspirin, it is essential to consider both the safety and potential interactions of these drugs.

Aspirin (Acetylsalicylic Acid) is commonly used for its analgesic, anti-inflammatory, and antipyretic properties. In obstetrics, it is sometimes prescribed to pregnant women for various reasons, including the prevention of preeclampsia in high-risk patients, as well as for its potential benefits in improving placental blood flow. However, it is important to note that Aspirin is classified as a Category D medication in the third trimester, meaning there is evidence of risk to the fetus, particularly concerning bleeding complications during delivery.

Transamin (Tranexamic Acid) is primarily used to reduce or prevent excessive bleeding. It works by inhibiting the breakdown of fibrin, a protein involved in blood clotting. Tranexamic Acid is generally considered safe during pregnancy, particularly for managing bleeding issues, but it should be used under medical supervision.

In your case, where you are experiencing light vaginal bleeding and have a high-risk assessment for preeclampsia, the combination of these two medications should be approached with caution. While there is no direct contraindication to taking Aspirin and Tranexamic Acid together, the potential for increased bleeding risk must be considered. Aspirin can affect platelet function and prolong bleeding time, while Tranexamic Acid is intended to reduce bleeding. Therefore, the two medications may have opposing effects, which could complicate your clinical situation.

It is crucial to consult with your healthcare provider before taking these medications together. They can assess your specific situation, including the cause of your bleeding, your overall health, and any other medications you may be taking. Your doctor may decide to monitor your condition closely or adjust your treatment plan based on your needs.

In summary, while there is no definitive evidence suggesting that taking Aspirin and Tranexamic Acid together during pregnancy is harmful, the potential for increased bleeding risk and the specific context of your pregnancy necessitate a thorough discussion with your healthcare provider. Always prioritize open communication with your medical team regarding any medications you are considering during pregnancy, especially when complications such as bleeding are involved.

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