Medication Abortion: What to Expect and Common Concerns - Obstetrics and Gynecology

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Medical abortion


Hello, I found out I was 5 weeks pregnant on October 2nd.
I took the first dose of RU486 on October 4th and the second dose on October 6th.
When I returned to the obstetrics and gynecology clinic on October 7th, an ultrasound showed that the embryo was no longer visible.
The doctor then prescribed uterotonics for me.
During a follow-up appointment on October 16th, it was noted that there was still a 1 cm blood clot that had not been expelled.
However, on October 17th, I noticed a long object approximately 4 to 5 cm in length that looked like tissue when I went to the bathroom.
I would like to ask what this might be.

Lü Lü, 20~29 year old female. Ask Date: 2021/10/17

Dr. Cai Yonglong reply Obstetrics and Gynecology


The first to be expelled should be the fetal tissue, and what was expelled on 10/17 may be chorionic tissue (which will later develop into the placenta).
If there is still pain or bleeding, it is advisable to visit a gynecology clinic.

Reply Date: 2021/10/17

More Info


Medication abortion, also known as medical abortion, is a safe and effective method for terminating a pregnancy using medication. It typically involves a two-step process using two different medications: mifepristone (often referred to as RU486) and misoprostol. Understanding what to expect during this process and addressing common concerns can help alleviate anxiety and ensure a smoother experience.

In your case, you began the medication abortion process on October 4th, taking mifepristone, followed by misoprostol two days later. The ultrasound on October 7th indicated that the embryo was no longer visible, which is a positive sign that the medication was effective in terminating the pregnancy. Afterward, your doctor prescribed uterotonics to help expel any remaining tissue.

The tissue you observed on October 17th, measuring approximately 4 to 5 cm, is likely part of the pregnancy tissue that your body was expelling. During a medication abortion, it is common for individuals to pass blood clots and tissue as the uterus contracts and sheds its lining. The size and appearance of the tissue can vary, and it is not unusual for it to resemble a long, stringy mass. This is a normal part of the process, and many individuals experience similar occurrences.

Here are some common concerns and what to expect during a medication abortion:
1. Bleeding and Cramping: After taking misoprostol, you can expect to experience bleeding that may be heavier than a typical menstrual period. Cramping is also common as your uterus contracts to expel the contents. The intensity of cramping can vary, but over-the-counter pain relievers like ibuprofen can help manage discomfort.

2. Passing Tissue: As you have experienced, passing tissue is a normal part of the process. It can vary in size and consistency, and it is important to monitor the amount of bleeding. If you soak through two or more pads in an hour for two consecutive hours, you should contact your healthcare provider.

3. Follow-Up Care: It is crucial to have follow-up appointments with your healthcare provider to ensure that the abortion is complete and to address any concerns. Your doctor may perform an ultrasound or a physical exam to confirm that the uterus is clear of any remaining tissue.

4. Emotional Well-Being: It's normal to experience a range of emotions after a medication abortion. Some individuals may feel relief, while others may experience sadness or guilt. Seeking support from friends, family, or counseling services can be beneficial.

5. Potential Complications: While medication abortion is generally safe, complications can occur. Signs of complications include severe pain that is not relieved by medication, heavy bleeding, fever, or foul-smelling discharge. If you experience any of these symptoms, seek medical attention promptly.

6. Future Fertility: Many individuals are concerned about how a medication abortion may affect future pregnancies. Research indicates that medication abortion does not impact future fertility, and most individuals can conceive again shortly after the procedure.

In conclusion, the tissue you passed is likely a normal part of the medication abortion process. It is essential to stay in touch with your healthcare provider for follow-up care and to address any concerns you may have. Remember that you are not alone in this experience, and support is available to help you through this time. If you have further questions or concerns, do not hesitate to reach out to your healthcare provider for personalized guidance.

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