Uveitis: Treatment Options and Management Strategies - Ophthalmology

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How to treat iritis?


I was hit in the left eye by a stone when I was young, and later underwent surgery to remove the blood clot.
Everything has been fine for almost 40 years, but in the past six months, my left eye has frequently been swollen, painful, light-sensitive, and blurry.
Some doctors have said it is dry eye, but one doctor found white inflammatory cells during the examination and suggested it might be iritis.
I was prescribed steroid eye drops.
I have a few questions:
1.
If it is iritis, is it sufficient to only use steroid eye drops, or should I also have blood tests for autoimmune and rheumatic conditions and an aqueous humor analysis for cytomegalovirus?
2.
Besides steroid eye drops, should I also be using medications to relax the ciliary muscle and dilate the pupil?
3.
If I no longer have symptoms, does that mean the iritis has healed? Should I continue to have follow-up appointments?
4.
I have heard that iritis does not completely resolve and can only be managed to minimize flare-ups.
Is that true? Thank you for your response.

A-Wen, 40~49 year old female. Ask Date: 2021/11/01

Dr. Gao Pilin reply Ophthalmology


Hello, A-Wen: 1.
Simple iritis can be alleviated with steroid treatment; whether additional examinations are necessary depends on the physician's clinical diagnosis.
2.
Sometimes, it may not be necessary to use mydriatics, depending on the inflammation status.
3.
Occasionally, it is only a temporary relief, and it is uncertain when it may recur; if symptoms arise, follow-up is required.
4.
It may recur multiple times or may occur only once.
Please refer to https://bit.ly/3w7bE0x.

Reply Date: 2021/11/01

More Info


Uveitis, particularly iritis (inflammation of the iris), can be a complex condition requiring careful management and treatment. Given your history of trauma to the left eye and the recent symptoms you've described—pain, light sensitivity, and blurred vision—it's understandable that you are seeking clarity on your treatment options and management strategies.

1. Treatment with Steroid Eye Drops: If your diagnosis is indeed iritis, topical corticosteroids like the one you mentioned (e.g., prednisolone acetate) are commonly prescribed to reduce inflammation. However, the necessity of further testing, such as blood tests for autoimmune conditions or aqueous humor analysis for viral infections (like cytomegalovirus), depends on the clinical context. If your uveitis is classified as "idiopathic" (without a known cause), the doctor may initially treat with steroids and monitor your response. However, if there are concerns about underlying systemic conditions or if the uveitis is recurrent, further investigations may be warranted.

2. Additional Medications: In addition to corticosteroids, it is indeed common practice to use medications that dilate the pupil (mydriatics) and relax the ciliary muscle (cycloplegics). These medications help alleviate pain by preventing muscle spasms and reducing light sensitivity. They also help prevent complications such as synechiae (adhesions between the iris and lens), which can occur in cases of uveitis.

3. Monitoring Symptoms: The absence of symptoms does not always equate to complete resolution of the inflammation. Uveitis can have periods of exacerbation and remission. Therefore, even if you feel better, it is crucial to follow up with your ophthalmologist. Regular monitoring can help ensure that any recurrence is caught early and managed appropriately. Your doctor may recommend follow-up visits at specific intervals, especially if you have a history of recurrent uveitis.

4. Chronic Nature of Uveitis: It is true that some forms of uveitis can be chronic or recurrent, meaning that while they can be controlled with treatment, they may not be completely curable. The goal of treatment is to manage symptoms, reduce inflammation, and prevent complications, such as cataracts or glaucoma, which can arise from both the inflammation itself and the long-term use of corticosteroids.

In summary, while steroid eye drops are a primary treatment for iritis, the management of uveitis often requires a comprehensive approach that may include additional medications and regular monitoring. If you experience any new symptoms or if your current symptoms worsen, it is essential to contact your healthcare provider promptly. They can provide tailored advice based on your specific situation and medical history. Always remember that managing uveitis effectively often involves a partnership between you and your healthcare team, ensuring that you receive the best possible care.

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