Hepatitis B Fibrosis: Which Doctor's Advice to Trust? - Gastroenterology and Hepatology

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Hepatic fibrosis due to hepatitis B?


Hello Doctor, I am a carrier of Hepatitis B and have been regularly monitored at a gastroenterology clinic in Chiayi.
Recently, during an ultrasound examination, the clinic doctor informed me that there appears to be some fibrosis in my liver, although my liver function and AFP levels are normal.
Concerned about this, I went for a free ultrasound examination organized by the Hepatitis Foundation on October 3rd, where a physician from Chiayi personally examined me and reported that my abdominal ultrasound (liver) was normal.
Which doctor should I trust? Should I undergo further tests at the hospital? Thank you!

Xiao Zhuang, 40~49 year old female. Ask Date: 2021/11/01

Dr. Chen Shidian reply Gastroenterology and Hepatology


Ultrasound is influenced by personal interpretation and machine resolution, raising concerns about the accuracy of biopsy or self-paid liver fibrosis scans (approximately around NT$1,000).

Reply Date: 2021/11/01

More Info


When it comes to managing Hepatitis B, particularly for those who are carriers or have been diagnosed with liver fibrosis, it is crucial to have a clear understanding of the condition and the implications of various medical opinions. In your case, you have received conflicting reports regarding the state of your liver, specifically concerning fibrosis. One doctor indicated that there is some fibrosis, while another stated that your liver appears normal upon ultrasound examination.

First and foremost, it is important to understand that liver fibrosis is a progressive condition that can lead to cirrhosis and liver cancer if not monitored and managed properly. The presence of fibrosis indicates that there has been some level of liver damage, which can be caused by chronic Hepatitis B infection. However, the degree of fibrosis can vary significantly, and not all patients with Hepatitis B will progress to severe liver disease.

In terms of which doctor's advice to trust, it is advisable to consider a few factors:
1. Experience and Specialization: Ensure that the doctor you are consulting specializes in hepatology or gastroenterology, as they will have more expertise in managing liver diseases. If you have seen a general practitioner or a less specialized doctor, it may be beneficial to seek a second opinion from a hepatologist.

2. Diagnostic Methods: Ultrasound is a common non-invasive method to assess liver health, but it may not always detect early stages of fibrosis accurately. Other diagnostic tools, such as FibroScan (transient elastography), MRI elastography, or liver biopsy, can provide more definitive information regarding the degree of fibrosis. If there is uncertainty, asking for these additional tests can help clarify the situation.

3. Consistency of Results: If two different doctors provide conflicting information, it may be worth considering the context of their assessments. For instance, the quality of the ultrasound equipment, the experience of the technician, and the specific criteria used to evaluate the liver can all influence results.
4. Follow-Up and Monitoring: Regardless of the current state of your liver, regular monitoring is essential. This typically includes routine blood tests to check liver function (such as ALT, AST, and bilirubin levels), as well as periodic imaging studies to monitor any changes in liver structure.

5. Patient History: Your personal health history, including any symptoms you may be experiencing (fatigue, jaundice, abdominal pain), should also be taken into account. If you have symptoms that suggest liver dysfunction, this may warrant more aggressive investigation.

In conclusion, it is crucial to have a comprehensive approach to your health management. If you feel uncertain about the advice you have received, seeking a third opinion from a reputable liver specialist may provide clarity. Additionally, discussing the possibility of more advanced diagnostic tests can help ensure that you have a complete understanding of your liver health. Remember, managing Hepatitis B effectively involves not only monitoring liver health but also considering antiviral treatment if indicated, lifestyle modifications, and regular follow-ups to prevent complications.

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