PET Scan Results: Navigating Uncertainty in Throat Symptoms - Nuclear Medicine

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Positron Emission Tomography (PET) Report Issues


Hello Doctor, I have a question that I would like to ask.
I feel very helpless and do not know how to deal with the persistent sensation of pain and foreign body feeling in my throat.
I have undergone the following examinations: in April, I had a bilateral tonsillectomy and uvulopalatoplasty.
I am unsure if this is a postoperative complication, but the surgeon mentioned that my wounds were healing well.
Over the past six months, I have had a nasopharyngoscopy, gastroscopy, thyroid ultrasound, and MRI of the head and neck, all of which did not reveal any significant issues.
However, the sensation of a foreign body and pain in my throat has persisted 24/7, and I experience sudden sharp pain even when I am not eating or speaking.
I am very worried that there may be an underlying issue that has not been identified, so I underwent a PET scan.
The report indicated that there may be a lesion in the area of the base of the tongue and epiglottis, but the doctor could not confirm whether there are cancer cells; it could be a physiological change, but the possibility of a malignant tumor cannot be ruled out.
I found some information online regarding the SUV values, and the report states an SUVmax of 4.9, which is concerning since a value over 2.5 is more likely to indicate the presence of cancer cells.
I am very scared and worried, and if there is a problem, I hope to address it as soon as possible to prolong my life, especially since I have a 3-year-old child at home.
I am truly frightened and helpless.
I am attaching the report and hope you can provide some advice on what I should do.
Thank you.
I have previously visited an ENT specialist at a health checkup hospital, but the doctor assured me that there was no issue.
However, my symptoms persist, and I remain very concerned.
I consulted another hospital, and the doctor mentioned that the epiglottis appears hypermetabolic on the report.
To confirm, the entire section would need to be excised, but that is a major surgery.
Alternatively, they could take a biopsy of the most hypermetabolic area, but they cannot guarantee that the non-biopsied areas are free of issues.
I truly do not know how to ascertain whether there is any pathological change or cancer cells.
Would a biopsy be meaningful in confirming the presence of cancer cells? I seek your help, thank you.

Miss Lin, 40~49 year old female. Ask Date: 2021/11/03

Dr. Zhuang Zhijian reply Nuclear Medicine


If a biopsy is performed and tissue samples are obtained, staining the tissue and conducting histopathological examination under a microscope can assist in diagnosis and serve as a basis for further treatment.
It is recommended to discuss this with an otolaryngologist.

Reply Date: 2021/11/03

More Info


I understand that you are experiencing significant anxiety regarding your throat symptoms and the results of your recent PET scan. It's completely normal to feel overwhelmed when faced with health uncertainties, especially when it involves potential malignancies. Let’s break down your situation and provide some clarity on the findings and next steps.

From your description, it seems you have undergone a thorough evaluation, including tonsillectomy, endoscopies, and imaging studies, all of which have not revealed any clear abnormalities. However, the persistent sensation of a foreign body and pain in your throat is understandably distressing. The PET scan results indicating a maximum standardized uptake value (SUVmax) of 4.9 in the area around the base of the tongue and epiglottis is concerning, particularly since values above 2.5 can suggest increased metabolic activity, which may be associated with malignancy.

It’s important to note that while elevated SUV values can be indicative of cancer, they are not definitive on their own. Various benign conditions, such as infections or inflammatory processes, can also lead to increased uptake. Therefore, the interpretation of these results must be done in conjunction with your clinical history, physical examination findings, and other diagnostic tests.

Given the uncertainty surrounding your condition, here are some recommendations on how to proceed:
1. Consultation with an Oncologist: Given the PET scan findings, it would be prudent to consult with an oncologist who specializes in head and neck cancers. They can provide a more comprehensive evaluation and discuss the implications of the PET results in the context of your symptoms and medical history.

2. Consider a Biopsy: If the oncologist deems it necessary, a biopsy of the area with the increased uptake may be recommended. This procedure can provide definitive information regarding the presence of cancer cells. While it is an invasive procedure, it can be crucial for accurate diagnosis and subsequent management.

3. Follow-Up Imaging: Depending on the oncologist's assessment, additional imaging studies, such as an MRI or CT scan, may be warranted to further evaluate the area of concern and to assess for any potential spread or involvement of surrounding tissues.

4. Symptom Management: In the meantime, managing your symptoms is essential. Discuss with your healthcare provider about options for pain relief and any other supportive measures that can help alleviate your discomfort.

5. Emotional Support: It’s also vital to address the emotional toll that this situation is taking on you. Consider seeking support from a mental health professional or joining a support group for individuals facing similar health concerns. This can provide you with coping strategies and a safe space to express your fears and anxieties.

6. Stay Informed but Cautious: While it’s natural to seek information online, be cautious about the sources you consult. Misinformation can exacerbate anxiety. Focus on credible medical resources and discussions with your healthcare team.

In conclusion, while the PET scan results raise valid concerns, they do not provide a definitive diagnosis. Engaging with specialists who can guide you through the next steps is crucial. Remember, early detection and intervention are key in managing any potential health issues. You are not alone in this journey, and there are professionals ready to support you through it.

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