Do You Need to Stop Medications or Fast Before a Fecal Occult Blood Test? - Gastroenterology and Hepatology

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Is there a need to stop any medications or fast from certain foods before undergoing a fecal occult blood test using immunochemical methods?

Wu Mei-hsin, 30~39 year old female. Ask Date: 2021/11/08

Dr. Chen Shidian reply Gastroenterology and Hepatology


No need to stop the medication, maintain a normal diet.

Reply Date: 2021/11/08

More Info


When preparing for a fecal occult blood test (FOBT), it is generally not necessary to stop any medications or fast before the test. The FOBT is designed to detect hidden blood in the stool, which can be an early sign of conditions such as colorectal cancer or other gastrointestinal issues.
The test can be affected by certain factors, but most medications do not interfere with the results. However, there are a few exceptions to be aware of. For instance, nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or aspirin can cause gastrointestinal bleeding, which may lead to false-positive results. If you are taking these medications regularly, it is advisable to discuss with your healthcare provider whether you should temporarily discontinue them prior to the test.

In terms of dietary restrictions, it is typically recommended to avoid certain foods that can also affect the test results. Foods such as red meat, certain vegetables (like turnips and radishes), and vitamin C supplements can lead to false positives or negatives. Therefore, it is often suggested to avoid these foods for at least 48 hours before the test. However, the specifics can vary based on the type of FOBT being used (e.g., guaiac-based vs. immunochemical tests), so it is essential to follow the instructions provided by your healthcare provider or the testing facility.

In summary, while you do not need to fast or stop most medications before a fecal occult blood test, it is wise to avoid certain foods and consult with your healthcare provider regarding any medications that may influence the results. Always follow the specific instructions given by your healthcare provider to ensure accurate test results. If you have any concerns or questions about your medications or dietary restrictions, do not hesitate to reach out to your healthcare provider for personalized advice.

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