Managing Long-Term Effects of Acute Conjunctivitis on Vision - Ophthalmology

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Post-acute conjunctivitis sequelae


Doctor, after I developed acute conjunctivitis last year, I have residual effects on my cornea, resulting in white spots that blur my vision.
The white spots disappear with steroid eye drops, but they reappear once I stop the medication.
This has been ongoing for a year.
I would like to know if there are other treatment options besides steroid eye drops.
I have a family history of glaucoma, so I am quite concerned.
If I continue using the eye drops, how often should I return for follow-up appointments? If the white spots disappear and I stop the medication only for them to recur, will this lead to drug resistance? Is it common for someone to have symptoms for over a year without recovery? Thank you for your answers, Doctor!

Ms. Li, 30~39 year old female. Ask Date: 2021/11/11

Dr. Gao Pilin reply Ophthalmology


Hello, Ms.
Li: This type of keratitis should be treated with corticosteroids.
Corticosteroids are not antibiotics and do not lead to antibiotic resistance.
If there is no elevated intraocular pressure during follow-up visits, it typically will not cause glaucoma.
You can return for a follow-up during an episode.
Such cases are relatively rare, so you may want to consult your attending physician for more details.

Reply Date: 2021/11/11

More Info


Managing long-term effects of acute conjunctivitis, particularly when it leads to complications such as corneal scarring or opacities, can be challenging. Your experience with persistent white spots affecting your vision after an episode of acute conjunctivitis is not uncommon. These white spots, often referred to as corneal opacities or scars, can result from inflammation and damage to the corneal epithelium during the conjunctivitis episode.


Understanding Corneal Opacities
Corneal opacities can significantly impact vision, depending on their size, location, and depth. If they are located in the visual axis (the central part of the cornea), they are more likely to cause noticeable vision problems. The fact that you have been using steroid eye drops to manage these opacities indicates that inflammation is a significant factor in your condition. Steroids can help reduce inflammation and promote healing, but they must be used cautiously, especially in patients with a family history of glaucoma.


Alternative Treatment Options
In addition to steroid eye drops, there are several other treatment options that may be considered:
1. Artificial Tears: If you experience dryness or discomfort, using preservative-free artificial tears can help maintain moisture on the surface of the eye and improve comfort.

2. Antiviral or Antibiotic Drops: If there is a suspicion of a viral or bacterial component contributing to your symptoms, your doctor may prescribe antiviral or antibiotic drops.

3. Amniotic Membrane Therapy: This involves placing a human amniotic membrane over the affected area of the cornea to promote healing and reduce inflammation.

4. Scleral Lenses: These specialized contact lenses can help protect the cornea and improve vision by creating a smooth optical surface over irregularities.

5. Surgical Options: In cases where opacities are severe and vision is significantly affected, surgical interventions such as corneal transplantation may be considered.


Monitoring and Follow-Up
Given your family history of glaucoma, it is crucial to have regular follow-ups with your ophthalmologist. The frequency of visits can vary based on your specific situation, but a common recommendation is every 3 to 6 months. Your doctor will monitor the condition of your cornea, the effectiveness of the treatment, and any potential side effects from long-term steroid use.


Concerns About Resistance and Recurrence
Regarding your concern about developing resistance to steroid drops, it is essential to understand that while prolonged use of steroids can lead to complications such as increased intraocular pressure (which can lead to glaucoma), they do not typically lead to drug resistance in the same way antibiotics do. However, the risk of side effects increases with prolonged use, which is why your doctor may recommend tapering off the medication once your symptoms improve.


Long-Term Recovery
It is not uncommon for patients to experience symptoms for an extended period, sometimes over a year, especially if the initial inflammation was severe. The healing process can be slow, and while some patients may eventually see significant improvement, others may continue to experience residual effects. It is vital to maintain open communication with your healthcare provider about your symptoms and any changes you notice.

In conclusion, managing the long-term effects of acute conjunctivitis requires a comprehensive approach that includes monitoring, potential alternative treatments, and regular follow-ups. Your concerns about glaucoma and the long-term use of steroids are valid and should be discussed with your ophthalmologist to tailor a treatment plan that minimizes risks while effectively managing your symptoms.

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