the Nine-Valent HPV Vaccine for Adolescents

Q: the Nine-Valent HPV Vaccine for Adolescents

Hello, the questioner： According to the vaccine information approved by the Ministry of Health and Welfare's Food and Drug Administration, the number of doses for different vaccine types and target populations may vary (please refer to the vaccination schedule table on page 7). <

Inquiry about the nine-valent cervical cancer vaccine?

Hello, Director: I would like to ask if a junior high school student aged 13-14 who wishes to receive the nine-valent HPV vaccine only needs two doses.
If they are over 15 years old, do they need to receive a third dose? Additionally, can the interval between the second dose be just two months? Thank you.

Jane, 40~49 year old female. Ask Date: 2021/11/19

Dr. Zhang Kunmin reply Obstetrics and Gynecology

Hello, the questioner: According to the vaccine information approved by the Ministry of Health and Welfare's Food and Drug Administration, the number of doses for different vaccine types and target populations may vary (please refer to the vaccination schedule table on page 7).
For example, for middle school girls: (1) For the Gardasil HPV vaccine, those aged 9-14 at the time of the first dose only require 2 doses, while those aged 15 and older need 3 doses.
(2) For the Gardasil 4-valent HPV vaccine, individuals aged 9-13 at the time of the first dose can receive 2 doses, while those aged 14 and older need 3 doses.
Males aged 9-26 at the time of the first dose require 3 doses, but due to the discontinuation of the 4-valent vaccine, it will no longer be available in the self-paid market starting in the first quarter of 2021.
(3) For the Gardasil 9-valent HPV vaccine, individuals aged 9-14 only need 2 doses, while those aged 15 and older require 3 doses.
For the 9-valent Gardasil HPV vaccine: (1) Males and females aged 9-14: receive 2 doses at 0 and 6-12 months.
(2) Males and females aged 15-45: receive 3 doses at 0, 2, and 6 months.
If receiving 2 doses, the second dose should be administered at the 6-month mark (at least 5 months after the first dose), but if the interval is less than 5 months, 3 doses must be administered.
Thank you! Wishing you peace and health.
Dr.
Zhang

Reply Date: 2021/11/19

More Info

The Nine-Valent HPV Vaccine, known as Gardasil 9, is a significant advancement in the prevention of human papillomavirus (HPV) infections, which can lead to various cancers and genital warts. Understanding the vaccination schedule and requirements for adolescents is crucial for ensuring effective protection against HPV.

For adolescents aged 13 to 14 years, the vaccination schedule for Gardasil 9 is indeed different compared to those who are older. According to the guidelines set by health authorities, individuals in this age group are recommended to receive only two doses of the vaccine. The first dose can be administered at any time, and the second dose should be given 6 to 12 months after the first dose. This two-dose schedule is designed to provide adequate immune response and protection against the types of HPV covered by the vaccine.

However, once an individual turns 15 years old, the vaccination protocol changes. For those aged 15 and older, a three-dose schedule is required. The first dose is given at the initial visit, the second dose is administered two months later, and the third dose is given six months after the first dose. This adjustment is based on research indicating that older adolescents and adults may require a more robust immune response, which is achieved through the additional dose.

Regarding the interval between doses, it is important to adhere to the recommended timing. While the second dose can be given as early as two months after the first dose, it is generally advised to wait at least six months to ensure optimal immune response. If the second dose is administered too soon, it may not provide the intended level of protection, and the individual may need to restart the vaccination series.

In summary, for adolescents aged 13 to 14 years, two doses of the Nine-Valent HPV Vaccine are sufficient, with the second dose given 6 to 12 months after the first. For those who are 15 years or older, a three-dose series is required. It is crucial to follow the recommended intervals to maximize the vaccine's effectiveness. Parents and guardians should consult with healthcare providers to ensure their children receive the appropriate vaccinations at the right times, contributing to the overall goal of reducing HPV-related diseases in the population.

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