Impact of Taking Medications in the Morning vs. Evening for Anxiety - Psychiatry

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Does it make a difference whether Bedoshu is taken in the morning or at night?


Due to autonomic nervous system dysfunction, I experience palpitations, hand tremors, and anxiety.
My previous doctor prescribed one tablet of Propranolol at night and one tablet of Fluoxetine in the morning and evening.
I have been on this medication for over six months, but recently, after moving to a new environment, my anxiety and depression have worsened.
My main complaint during previous visits was to avoid hand tremors and lack of concentration while working during the day.
It took several trials before settling on the current regimen.

Recently, after moving and switching to a new clinic, the new doctor prescribed one tablet of Betahistine in the morning and half a tablet of Olanzapine as needed in the morning and evening.
However, Propranolol and Betahistine should be similar medications, right? Will switching to taking it in the morning make my hand tremors worse while I work? I feel a bit uneasy about suddenly changing from Fluoxetine after taking it for over six months.
If I take half a tablet of Olanzapine in the morning, will it affect my concentration?

Dao Dao, 20~29 year old female. Ask Date: 2021/11/27

Dr. Zhang Fangrong reply Psychiatry


Hello, in response to your previous inquiry, Bipolar and Beteshu are the same medication, just manufactured by different companies.
Although the names differ, the active ingredients are the same.
This type of medication is commonly prescribed for daytime use; however, it can also be taken before bedtime as long as there are no significant adverse effects, particularly those affecting sleep.

Additionally, Fuanyuan and Olanzapine are different medications that belong to the sedative and anxiolytic class, and their actions and effects are similar.
Therefore, if switching medications improves your discomfort, it is considered an appropriate choice.
Of course, if you experience any discomfort, please discuss with your physician whether to adjust the dosage or switch medications, as these options can be arranged.
Wishing you peace of mind and well-being.

Best regards,
Zhang Fangrong
Department of Psychiatry

Reply Date: 2021/11/27

More Info


The impact of taking medications for anxiety, particularly in the context of timing—morning versus evening—can be significant and varies based on the specific medications involved, their pharmacokinetics, and the individual’s unique response to treatment. In your case, you have been prescribed different medications, including Bupropion (必博寧), which is often used for depression and anxiety, and other medications like Betahistine (倍得舒) and Olanzapine (歐慮平), which have different mechanisms of action.


Understanding the Medications
1. Bupropion (必博寧): This medication is primarily an antidepressant that can also help with anxiety. It works by inhibiting the reuptake of norepinephrine and dopamine, which can enhance mood and energy levels. It is typically taken in the morning to avoid insomnia, as it can be stimulating for some individuals.

2. Betahistine (倍得舒): This medication is often used to treat vertigo and balance disorders. It works by improving blood flow to the inner ear. While not primarily an anxiolytic, it may help with symptoms related to anxiety that manifest physically, such as dizziness.

3. Olanzapine (歐慮平): This is an atypical antipsychotic that can be used to treat mood disorders and anxiety. It has sedative properties, which is why it is often prescribed in the evening.


Timing of Medication
The timing of when you take these medications can influence their effectiveness and side effects:
- Morning Dosing: Taking medications like Bupropion in the morning can help manage anxiety symptoms throughout the day, particularly if you experience issues like hand tremors or difficulty concentrating. However, if you find that taking it in the morning exacerbates your symptoms, it may be worth discussing with your doctor.

- Evening Dosing: Medications that have sedative effects, such as Olanzapine, are typically taken in the evening to help with sleep and to minimize daytime sedation. If you switch from taking it in the evening to the morning, you might experience increased anxiety or tremors during the day, especially if your body is not accustomed to the change.


Concerns About Medication Changes
You mentioned feeling uneasy about the switch from Fuan Yuan (福安源) to Betahistine. It’s important to communicate these feelings with your healthcare provider. Changes in medication can lead to fluctuations in how you feel, and it’s crucial to monitor your symptoms closely. If you notice increased anxiety, tremors, or difficulty concentrating after the change, these are valid concerns to bring up with your doctor.


Potential Side Effects
- Increased Tremors: If you are sensitive to changes in your medication regimen, switching to a morning dose of a stimulant medication like Bupropion could potentially increase tremors or anxiety symptoms, especially if you are already experiencing anxiety due to environmental changes, such as moving.

- Concentration Issues: Taking Olanzapine in the morning could lead to sedation and decreased concentration, which might not be ideal for your work environment. If you find that your attention is compromised, it may be necessary to adjust the timing or dosage.


Conclusion
In summary, the timing of anxiety medications can significantly impact their effectiveness and your overall well-being. It’s essential to have open communication with your healthcare provider about your symptoms, medication changes, and any concerns you have regarding your treatment plan. Adjustments may be necessary to find the right balance that allows you to manage anxiety effectively while maintaining focus and minimizing side effects. Always consult your doctor before making any changes to your medication regimen.

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