Medication for Gastrointestinal Issues After Vaccination - Gastroenterology and Hepatology

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Medication issues


Doctor, after receiving my first vaccine dose, I experienced gastrointestinal issues.
I underwent an ultrasound and endoscopy, which only indicated reflux.
Later, I occasionally felt bloating in either my upper or lower abdomen, and sometimes discomfort, though it’s not frequent.
Sometimes it resolves on its own.
The doctor prescribed Selina enteric-coated tablets for three months.
I noticed that the clinical uses do not mention anything related to bloating.
Is it appropriate for the doctor to prescribe this medication? Does this medication also have a function for relieving bloating? Thank you for your response.

Jayen288, 40~49 year old female. Ask Date: 2021/12/02

Dr. Chen Shidian reply Gastroenterology and Hepatology


It should be a medication for adjusting peristalsis; it can be tried and its efficacy evaluated.

Reply Date: 2021/12/02

More Info


When considering gastrointestinal issues following vaccination, it is essential to understand the potential interactions between medications and the body's response to vaccines. In your case, you experienced gastrointestinal discomfort after receiving your first COVID-19 vaccine dose, which led to further evaluations, including ultrasound and endoscopy. The findings indicated gastroesophageal reflux disease (GERD), which can contribute to symptoms such as bloating and discomfort in the abdominal area.

The medication prescribed to you, Selina enteric-coated tablets, is primarily used to help regulate gastrointestinal motility. While it may not be explicitly indicated for bloating, it can indirectly alleviate some symptoms associated with gastrointestinal dysmotility, which might be contributing to your discomfort. The mechanism of action for such medications often involves enhancing the movement of food through the digestive tract, which can help reduce feelings of fullness and bloating.

It's important to note that gastrointestinal symptoms can be multifactorial, especially after vaccination. Vaccines can sometimes trigger immune responses that may lead to transient gastrointestinal symptoms, including nausea, diarrhea, or abdominal discomfort. These symptoms are generally self-limiting and resolve as the body adjusts to the vaccine. However, if you have pre-existing gastrointestinal conditions, such as GERD or functional dyspepsia, these may be exacerbated by the stress of vaccination or the immune response.

In your situation, it would be prudent to monitor your symptoms while taking Selina. If you find that your bloating and discomfort persist or worsen, it may be beneficial to consult with your healthcare provider. They might consider adjusting your treatment plan or exploring other therapeutic options that specifically target bloating, such as simethicone or dietary modifications.

Dietary changes can also play a significant role in managing gastrointestinal symptoms. Keeping a food diary to identify any potential triggers can be helpful. Common culprits for bloating include high-fiber foods, carbonated beverages, and certain dairy products. Additionally, eating smaller, more frequent meals rather than large meals can help reduce the burden on your digestive system.

If your symptoms continue despite medication and dietary adjustments, further evaluation may be warranted. Conditions such as irritable bowel syndrome (IBS) or functional dyspepsia could be considered, especially if your symptoms are chronic and not solely related to the recent vaccination.

In summary, while the medication prescribed to you may not directly address bloating, it can help improve gastrointestinal motility, which may alleviate some of your discomfort. It is essential to maintain open communication with your healthcare provider regarding your symptoms and treatment efficacy. If necessary, they can provide additional guidance or alternative treatments tailored to your specific needs. Remember that managing gastrointestinal symptoms often requires a comprehensive approach, including medication, dietary adjustments, and lifestyle changes.

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