Interactions Between Contraceptive Pills and Common Medications - Pharmacology

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Interactions of Emergency Contraceptive Pills


Will the regular use of Qlaira (combined oral contraceptive) interact with the following medications and affect its contraceptive efficacy? (1) Flupine (Fluphenazine) (2) Eslam (Eszopiclone) Thank you, doctor!

cherry, 20~29 year old female. Ask Date: 2021/12/22

Dr. Zheng Shuwen reply Pharmacology


Hello, regarding your inquiry, here is the response: Based on database research, the oral contraceptive "Qilian" may interact with flupine (Fuanyuan tablets) and eslam (Yilemian), potentially altering the blood concentrations of Fuanyuan and Yilemian.
It is advised that during the medication period, you carefully read the drug label instructions and pay attention to your body's reactions.
If you experience any discomfort or have further questions, please consult your physician or pharmacist.
If you have any other questions, feel free to call during business hours.
Thank you.
Consultation phone number: 03-3698553.
Business hours: Monday to Tuesday: 08:30 AM - 10:00 PM; Wednesday to Friday: 08:30 AM - 06:00 PM; Saturday: 08:30 AM - 02:00 PM.

Reply Date: 2021/12/22

More Info


When considering the interactions between contraceptive pills, such as Qlaira (祈麗安), and other medications, it is essential to understand how these drugs can affect each other's efficacy and safety. In your case, you are inquiring about the potential interactions between Qlaira and two specific medications: Flupine (福安源錠) and Eslam (伊樂眠).

1. Qlaira (祈麗安):
Qlaira is a combined oral contraceptive pill that contains both estrogen and progestin. It works primarily by preventing ovulation, thickening the cervical mucus to block sperm, and thinning the uterine lining to prevent implantation. The effectiveness of Qlaira can be influenced by other medications, particularly those that induce liver enzymes, which can increase the metabolism of the hormones in the contraceptive pill.

2. Flupine (福安源錠):
Flupine is an antipsychotic medication that is often used to treat schizophrenia and other mental health disorders. It is not known to have a significant interaction with hormonal contraceptives like Qlaira. However, any medication that affects the central nervous system can have side effects that might indirectly influence adherence to the contraceptive regimen, such as sedation or cognitive impairment. Therefore, while Flupine does not directly affect the efficacy of Qlaira, it is essential to monitor any side effects that could impact your overall health and medication adherence.

3. Eslam (伊樂眠):
Eslam is a medication commonly used for sleep disorders, often containing ingredients that promote sedation. Similar to Flupine, Eslam does not have a known interaction with hormonal contraceptives. However, it is crucial to be cautious with any sedative medications, as they can affect your alertness and ability to manage daily activities. While Eslam itself does not reduce the effectiveness of Qlaira, the combination of sedatives and hormonal contraceptives should be monitored for any potential side effects.

Conclusion and Recommendations:
Based on the current understanding of drug interactions, neither Flupine nor Eslam is expected to significantly impact the effectiveness of Qlaira. However, it is always advisable to consult with your healthcare provider or pharmacist regarding any new medications you are considering or currently taking. They can provide personalized advice based on your health history and any other medications you may be using.

Additionally, it is important to maintain consistent use of your contraceptive pill as prescribed. If you experience any unusual side effects or have concerns about the effectiveness of your contraceptive method while taking these medications, do not hesitate to reach out to your healthcare provider for further evaluation and guidance.

In summary, while Flupine and Eslam do not have direct interactions with Qlaira, always prioritize open communication with your healthcare team to ensure safe and effective use of all medications.

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