Managing Insomnia After Discontinuing Lorazepam: What to Expect - Neurology

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I was prescribed Lexotan for my gastrointestinal pain caused by autonomic nervous system dysfunction. However, after stopping the medication, I still have insomnia and haven't improved. What should I do?


I previously took Lorazepam for over three months at a dosage of 0.5 mg before bedtime.
After discontinuing the medication, I experienced insomnia, which has persisted for four months now.
This insomnia is not caused by autonomic nervous system dysfunction; my symptoms of autonomic dysregulation were limited to stomach pain, nausea, and vomiting.
Interestingly, after stopping Lorazepam, my stomach pain symptoms have significantly decreased.
Before taking Lorazepam, I never had issues with insomnia.
The doctor who initially prescribed Lorazepam told me that taking it for life would not cause any problems.
However, my current doctor is unsure why my previous doctor recommended long-term use of Lorazepam.
He mentioned that there are many alternative medications available.
I am concerned about how long the insomnia after discontinuation will last.
(I tapered off the medication in three weeks and am unsure if that was too quick.) Currently, I am taking Dong Quai, but I can only sleep for 1-2 hours before waking up.
Although I can lie down and fall back asleep, I feel increasingly fatigued, and I lack energy during the day.
The doctor I am seeing now believes that my condition will gradually improve, so he prescribed a lighter medication, but I am uncertain how long it will take to return to my previous state.
I have read online that discontinuation can lead to poor sleep in the latter half of the night, and it may last for months or even years.
Seeing this information makes me wonder how much longer I can endure this or if I should return to taking Lorazepam.
I hope the doctor can provide some answers, and I would be very grateful.

Xiao Hao, 30~39 year old female. Ask Date: 2021/12/27

Dr. Hong Weibin reply Neurology


Hello: If you have been taking "Lunesta" for a period of time and experience rebound insomnia after discontinuation, it is recommended to try a gradual tapering method.
For example: take one pill today, half a pill tomorrow, one pill the day after, and half a pill the day after that, alternating in this manner.
After about one month, you can switch to taking half a pill daily.
After another month, you can alternate between half a pill, not taking any, and half a pill.

Reply Date: 2021/12/27

More Info


Managing insomnia after discontinuing Lorazepam can be a challenging process, especially when the medication was used for an extended period. Your experience of insomnia following the cessation of Lorazepam is not uncommon, as benzodiazepines like Lorazepam can lead to dependence and withdrawal symptoms, including sleep disturbances.
When you stop taking Lorazepam, your body may go through a withdrawal phase, which can manifest as increased anxiety, restlessness, and insomnia. The timeline for recovery varies among individuals, but it is generally accepted that withdrawal symptoms can last anywhere from a few days to several weeks. In some cases, particularly with prolonged use, individuals may experience lingering effects that can last for months.
You mentioned that you stopped taking Lorazepam after three weeks of tapering off, which is a relatively quick discontinuation. While some people can taper off benzodiazepines without significant issues, others may find that a slower tapering process is more beneficial in minimizing withdrawal symptoms. It’s essential to work closely with your healthcare provider to determine the best approach for your situation.

The fact that your gastrointestinal symptoms have improved after stopping Lorazepam is a positive sign, indicating that the medication may have contributed to those issues. However, the insomnia you are experiencing is understandably distressing. It’s important to recognize that insomnia can be multifactorial, influenced by psychological, physiological, and environmental factors.
Your current treatment with lighter medications may take time to show improvement. Antidepressants like Sertraline or Escitalopram can take several weeks to exert their full effects, and it’s not unusual for individuals to experience fluctuations in their sleep patterns during this period. It’s crucial to maintain open communication with your healthcare provider about your symptoms and any side effects you may be experiencing.

In terms of what to expect moving forward, many individuals find that their sleep gradually improves over time, especially with the right support and treatment plan. Cognitive Behavioral Therapy for Insomnia (CBT-I) is another effective approach that can help address the underlying issues contributing to your insomnia. This therapy focuses on changing the thoughts and behaviors that negatively impact sleep and can be particularly beneficial for those who have developed chronic insomnia.

Additionally, incorporating good sleep hygiene practices can also aid in improving your sleep quality. This includes maintaining a consistent sleep schedule, creating a comfortable sleep environment, limiting exposure to screens before bedtime, and avoiding stimulants like caffeine in the hours leading up to sleep.

If you find that your insomnia persists or worsens, it may be worth discussing the possibility of reintroducing a medication like Lorazepam with your doctor, but this should be approached cautiously and ideally as a short-term solution while exploring other therapeutic options.

In conclusion, managing insomnia after discontinuing Lorazepam can be a gradual process, and it’s essential to remain patient and proactive in your treatment. Collaborate closely with your healthcare provider, consider behavioral therapies, and maintain healthy sleep habits to support your recovery. Remember, you are not alone in this journey, and with time and the right strategies, improvement is possible.

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Dr. Lin Mianzhang reply Psychiatry
Hello, Xiao Cheng: Thank you for your hard work! It seems that your current insomnia may be a symptom of medication withdrawal. I recommend a gradual tapering approach to discontinue the medication, such as first reducing Lorazepam to half a tablet. If you can maintain stable sle...

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Hello, Xiao Hao: It is recommended to visit a neurologist to check for any abnormalities in neurological function.

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I previously took Lorazepam 0.5 mg for over three months, and stopping the medication has caused insomnia for more than nine months. I can fall asleep quickly, but I wake up after 2 to 3 hours, and when I go back to sleep, it’s always light sleep, making me feel increasingly fati...


Dr. Yu Quanxun reply Psychiatry
Hello, based on your description in the letter, you are experiencing stomach pain and autonomic nervous system dysfunction. You have previously taken Lexapro but have since discontinued it, and you are currently troubled by sleep issues, worrying that they may be a result of stop...

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I previously took Lorazepam 0.5 mg for over three months, and after stopping the medication, I have been experiencing insomnia for over nine months. I can fall asleep quickly, but I wake up after 2 to 3 hours, and when I go back to sleep, it's only light sleep, making me fee...


Dr. Wu Enliang reply Psychiatry
It may be advisable for users to consider using longer-acting benzodiazepines such as Clonazepam or Diazepam instead of Lorazepam, as they may facilitate easier discontinuation (but this should still be discussed with your physician), and to enhance sleep hygiene. Dr. Wu En-Liang...

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