Abnormal LDCT Results: Common Concerns and Follow-Up - Pulmonology

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Questions regarding abnormal findings in LDCT screening?


Hello Doctor, I would like to ask about my LDCT report from my health check-up, which shows the following two abnormalities: recommended follow-up in 3 months.
*Mild fibrosis in both lung apices with irregular pleural interface - likely due to chronic inflammation.
*Subpleural lines and shadows in both lungs - possibly indicative of nonspecific lung collapse, fibrosis, or inflammation.
I currently do not feel any issues with my lungs.
May I ask: 1.
Are these two abnormalities common? 2.
What are the possible causes? (Aging or...) 3.
If it is chronic inflammation, how can I promote healing? 4.
What is the reason for the recommended follow-up? Thank you, Doctor!

Feifei, 30~39 year old female. Ask Date: 2021/12/28

Dr. Wang Lanfeng reply Pulmonology


Hello: Based on your description, your LDCT report shows some nonspecific changes that generally only require observation and follow-up.
As for the cause, it may be due to past chronic inflammation.
In principle, these changes may not necessarily resolve, but they should not cause significant impact.
Therefore, regular monitoring for any changes is sufficient.
Thank you.

Reply Date: 2021/12/28

More Info


Hello! Thank you for reaching out with your concerns regarding your LDCT (Low-Dose Computed Tomography) report. It's understandable to feel anxious about abnormal findings, especially when it comes to lung health. Let's break down your questions one by one.

1. Are these two abnormalities common?
Yes, the findings of mild fibrosis and irregularities at the lung/pleural interface are relatively common, especially in individuals with a history of smoking, environmental exposures, or even in older adults due to natural aging processes. Fibrosis can occur as a result of previous infections, inflammation, or other lung conditions. The presence of subpleural lines and shadows may indicate non-specific changes, which could be due to various factors, including chronic inflammation or minor structural changes in the lung tissue.

2. What are the potential causes of these findings?
The causes of mild pulmonary fibrosis and irregularities can vary. Chronic inflammation is often a result of long-term exposure to irritants such as tobacco smoke, air pollution, or occupational hazards. Other potential causes include previous infections (like pneumonia), autoimmune diseases, or even idiopathic pulmonary fibrosis, which is a condition with no known cause. Aging can also contribute to changes in lung structure and function, leading to such findings.
3. How can I promote healing if it is chronic inflammation?
If chronic inflammation is suspected, there are several steps you can take to support lung health and potentially reduce inflammation:
- Avoid Irritants: If you smoke, quitting is the most significant step you can take. Additionally, try to minimize exposure to secondhand smoke, air pollution, and occupational hazards.

- Healthy Lifestyle: A balanced diet rich in antioxidants (fruits, vegetables, whole grains) can help combat inflammation. Regular exercise is also beneficial for lung function and overall health.

- Stay Hydrated: Drinking plenty of water can help thin mucus in the lungs, making it easier to clear.

- Follow Medical Advice: If your doctor prescribes medications or recommends specific treatments, be sure to follow their guidance closely.

4. Why is follow-up recommended?
The recommendation for a follow-up in three months is likely due to the need for monitoring any changes in your lung condition. Abnormal findings on imaging can sometimes indicate the beginning of a more serious issue, and regular follow-up allows your healthcare provider to track any progression or improvement. It also provides an opportunity to reassess your symptoms and adjust your management plan if necessary.
In summary, while the findings on your LDCT report may sound concerning, they are not uncommon and can often be managed effectively with lifestyle changes and regular monitoring. It’s essential to maintain open communication with your healthcare provider, who can guide you through the next steps and address any further concerns you may have. Remember, early detection and management are key to maintaining lung health. If you experience any new symptoms, such as persistent cough, shortness of breath, or chest pain, be sure to seek medical attention promptly.

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