SSRIs: Do They Heal or Just Delay Recovery? - Psychiatry

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SSRI Issues


1.
How do SSRIs actually help people recover? Do they only prolong the presence of serotonin in the brain, or do they also repair neural pathways? 2.
Does not taking medication lead to brain atrophy? Will it make me less intelligent? Will my memory deteriorate? P.S.
I have OCD, and while the medication has improved my symptoms, I still feel overall pain both before and after starting the medication.
After starting the medication, my life feels chaotic, and I don't understand why.
I really want to stop taking the medication, but discussing this with my doctor hasn't been helpful; the doctor suggests not changing the medication and to just reduce the dosage if I'm uncomfortable.
Additionally, I have an upcoming exam, and I feel like I'm going to fail again.
As a second-time test taker, I feel I don't have the right to fail, especially since I used to be a top student in my first-choice program in computer science.
I feel embarrassed to tell everyone that I'm doing poorly on my second attempt.
I don't know what to do; I'm really sorry for my jumbled thoughts that make this hard to understand.
Thank you.

A, 10~19 year old female. Ask Date: 2022/01/04

Dr. Qiu Junda reply Psychiatry


Hello.
The text suggests that you may be feeling overwhelmed and negative due to the pressure of the academic examination.
I hope the following advice can help you.

1.
SSRIs (Selective Serotonin Reuptake Inhibitors) are antidepressants that can also be used to treat obsessive-compulsive disorder.
They work by increasing serotonin levels in the brain to improve mood symptoms.
However, not taking medication will not cause your brain to shrink or make you less intelligent (sometimes this may just be a way to encourage medication use).
2.
Regarding medical treatment, please ensure you follow up with your physician for discussions about your medication.
If you experience moments of emotional distress while preparing for your exams, you can call the Ministry of Health and Welfare's 1925 hotline for assistance.
Wishing you success in your exams.

Reply Date: 2022/01/04

More Info


Understanding SSRIs (Selective Serotonin Reuptake Inhibitors) and their role in mental health treatment can be quite complex, especially for individuals dealing with conditions like obsessive-compulsive disorder (OCD). Let's break down your questions and concerns regarding SSRIs, their effects on the brain, and the implications of discontinuing their use.

1. How do SSRIs promote recovery?
SSRIs primarily work by increasing the levels of serotonin in the brain, a neurotransmitter that plays a significant role in mood regulation. By inhibiting the reuptake of serotonin, these medications allow more serotonin to remain available in the synaptic cleft, which can enhance mood and alleviate symptoms of depression and anxiety. While this mechanism is crucial for symptom relief, SSRIs do not directly "repair" brain neurons. Instead, they may contribute to neuroplasticity—the brain's ability to adapt and reorganize itself—which can lead to improvements in mood and cognitive function over time. Some studies suggest that long-term use of SSRIs may promote the growth of new neurons in certain brain regions, particularly the hippocampus, which is involved in memory and learning. However, the extent and clinical significance of this neurogenesis are still under investigation.

2. Does not taking medication lead to brain atrophy or cognitive decline?
The relationship between medication, brain health, and cognitive function is nuanced. While chronic untreated mental health conditions can lead to cognitive impairments and may affect brain structure over time, the act of not taking SSRIs does not inherently cause brain atrophy or make one "dumber." Cognitive decline is more closely associated with the severity and duration of untreated mental health issues rather than the absence of medication alone. However, if you are experiencing significant anxiety or OCD symptoms, these can indeed impact your cognitive functions, such as memory and concentration.

Regarding your experience with SSRIs and your feelings of confusion and distress, it's important to acknowledge that medication can have varying effects on individuals. While some may find relief from their symptoms, others may experience side effects that can feel overwhelming or disorienting. If you feel that the medication is causing more harm than good, it is crucial to communicate this with your healthcare provider. They can help you explore alternative treatment options, which may include adjusting the dosage, switching to a different medication, or considering non-pharmacological treatments such as cognitive-behavioral therapy (CBT) or other therapeutic modalities.

It's understandable to feel pressure, especially as you prepare for important exams. The fear of failure can exacerbate anxiety, making it even more challenging to focus and perform. Remember that your mental health is a priority, and it's okay to seek support from friends, family, or mental health professionals during this time.
In summary, SSRIs can be effective in managing symptoms of OCD and other mental health conditions by enhancing serotonin levels in the brain. However, they do not directly repair brain structures. The decision to continue or discontinue medication should be made collaboratively with your healthcare provider, considering both the benefits and any adverse effects you may be experiencing. If you're feeling overwhelmed, don't hesitate to reach out for support—whether through therapy, support groups, or trusted individuals in your life. Your well-being is paramount, and there are paths to recovery that can align with your needs and circumstances.

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