Urethral Stricture After Prostate Cancer Surgery - Urology

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Urethral stricture


Hello, Director Du.
After undergoing radical prostatectomy for prostate cancer, I developed urethral stricture and had a dilation procedure done.
However, two weeks later, I noticed that the urine stream has narrowed again.
The dilation process was very painful.
Is it necessary to continue this procedure indefinitely? Is it not curable? Thank you.

Tu, 60~69 year old female. Ask Date: 2022/01/11

Dr. Du Shixi reply Urology


Hello: Urethral stricture is prone to recurrence.
You may discuss treatment options with your physician, or consider dilation under anesthesia.
Wishing you good health.

Reply Date: 2022/01/11

More Info


Urethral stricture is a common complication that can occur after prostate cancer surgery, particularly after radical prostatectomy. This condition involves the narrowing of the urethra, which can lead to difficulties in urination, including a weak urine stream, urgency, and even urinary retention. Understanding the causes, treatment options, and long-term management strategies for urethral stricture is crucial for patients who have undergone prostate cancer surgery.


Causes of Urethral Stricture
Urethral strictures can develop due to several factors related to prostate cancer surgery:
1. Surgical Trauma: The surgical procedure itself can cause trauma to the urethra, leading to scar tissue formation. This is particularly common in radical prostatectomy, where the prostate and surrounding tissues are removed.

2. Radiation Therapy: If radiation therapy was part of the treatment plan, it could also contribute to urethral strictures due to tissue damage and fibrosis.

3. Infection and Inflammation: Post-operative infections can lead to inflammation and subsequent scarring of the urethra.

4. Catheterization: The use of urinary catheters during and after surgery can also irritate the urethra and contribute to stricture formation.


Treatment Options
The treatment for urethral stricture typically begins with less invasive methods and may escalate to more invasive procedures if necessary. Here are some common treatment options:
1. Dilation: This is the procedure you mentioned, where a doctor uses a dilator to widen the narrowed section of the urethra. While dilation can provide temporary relief, it may need to be repeated periodically, as it does not address the underlying scar tissue.

2. Urethrotomy: This surgical procedure involves cutting the stricture to relieve the narrowing. It can be effective but may also require repeat procedures.

3. Urethral Reconstruction: For more severe or recurrent strictures, a more complex surgical reconstruction may be necessary. This involves removing the stricture and reconstructing the urethra using tissue grafts.

4. Stenting: In some cases, a stent may be placed in the urethra to keep it open. However, stenting is less commonly used due to potential complications and discomfort.


Long-term Management
Unfortunately, urethral strictures can be a chronic issue, and some patients may experience recurrent strictures even after treatment. Here are some considerations for long-term management:
- Regular Follow-ups: Regular follow-up appointments with your urologist are essential to monitor the condition and address any recurrence of symptoms promptly.

- Lifestyle Modifications: Staying hydrated and avoiding irritants (like caffeine and alcohol) may help reduce urinary symptoms.

- Patient Education: Understanding the signs of recurrence (such as a weak stream or difficulty urinating) can help you seek timely intervention.

- Support Groups: Connecting with others who have experienced similar issues can provide emotional support and practical advice.


Conclusion
In summary, urethral stricture after prostate cancer surgery is a manageable but potentially chronic condition. While dilation can provide temporary relief, it may not be a permanent solution, and further interventions may be necessary. It is essential to work closely with your healthcare provider to develop a personalized management plan that addresses your specific needs and concerns. If you continue to experience significant discomfort or complications, discussing more invasive options or referral to a specialist in urethral reconstruction may be warranted.

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