Can HPV Reactivate After 10 Years? Risks During Pregnancy - Urology

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Even after more than 10 years without a recurrence, can the virus still remain in the body?


About ten years ago, I had an infection with genital warts, which I treated successfully.
Since then, I have undergone several Pap smear tests, all of which have been normal.
I would like to know if there is a possibility of recurrence after so many years.
How long can the virus that causes genital warts remain in the body? I am currently 34 weeks pregnant and have noticed some growths in my vagina.
Is it possible that this is a recurrence of genital warts, even after ten years? Could there be other conditions that cause growths in the vagina? I am scheduled for a pelvic exam next week for Group B Streptococcus screening, and I will ask the doctor for a diagnosis.
However, I would like to know if there is a chance that it is not genital warts.
If it is indeed genital warts, what should I do?

Tang Guo, 30~39 year old female. Ask Date: 2022/01/14

Dr. Du Shixi reply Urology


Hello: 1) If warts are treated and the woman has undergone multiple internal examinations confirming recovery, the chances of recurrence after several years are low.
2) If warts are confirmed in the vagina, a cesarean section may be necessary (your obstetrician will discuss this with you).
As for other diseases, further examination may be needed to understand.
Wishing you good health.

Reply Date: 2022/01/14

More Info


Human Papillomavirus (HPV) is a common sexually transmitted infection that can lead to various health issues, including genital warts (often referred to as "cauliflower" or "condyloma") and cervical cancer. Your concerns about the potential reactivation of HPV after a decade, especially during pregnancy, are valid and warrant a thorough understanding of the virus and its implications.

Firstly, it is essential to recognize that HPV can remain dormant in the body for extended periods. While many individuals clear the virus naturally within two years, some may retain it in a latent state. This means that even after ten years without symptoms or abnormal Pap smear results, there is still a possibility that the virus could reactivate, particularly if there are changes in the immune system or other health factors. However, the likelihood of reactivation decreases significantly over time, especially if you have not experienced any recurrences or complications during the past decade.

Regarding your current pregnancy and the presence of new growths in the vaginal area, it is crucial to have these evaluated by your healthcare provider. While it is possible that these growths could be related to HPV (such as a recurrence of genital warts), there are numerous other conditions that could cause similar symptoms, including benign growths, infections, or other dermatological issues. The upcoming internal examination and Group B Streptococcus screening will provide your doctor with the opportunity to assess the situation more thoroughly.

If the growths are indeed identified as genital warts, the management will depend on their size, location, and any associated symptoms. Treatment options during pregnancy are limited but can include topical therapies that are considered safe for use in pregnant individuals. It is essential to discuss these options with your obstetrician or a specialist in maternal-fetal medicine to ensure the safety of both you and your baby.

Moreover, it is important to note that while HPV can be transmitted during childbirth, the risk of transmission is relatively low, and most infants born to mothers with HPV do not develop related health issues. However, in rare cases, some infants may develop respiratory papillomatosis, a condition where warts grow in the throat. This is a rare occurrence and should not be a cause for alarm, but it is something to discuss with your healthcare provider.

In summary, while the risk of HPV reactivation after ten years exists, it is relatively low, especially in the absence of any symptoms or abnormal test results. The new growths you are experiencing should be evaluated by your healthcare provider to determine their nature and appropriate management. Regular monitoring and communication with your healthcare team are crucial during pregnancy, particularly when there are concerns about HPV or any other health issues. Always prioritize open discussions with your healthcare provider to ensure the best outcomes for you and your baby.

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