Retinal Vein Occlusion and Its Impact on Eye Health - Ophthalmology

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Vascular obstruction-related issues?


Hello Doctor: I recently went for an eye examination and found that I have a retinal vein occlusion in my left eye, which has led to retinal hemorrhage.
I am seeing small black spots when looking at things.
I am currently waiting for a fundus photography examination, so the issue has not yet been addressed.
Additionally, I have severe chronic kidney disease and have not started dialysis yet.
I also have anemia; previously, I received erythropoietin injections every two weeks, but for the past two months, I have switched to receiving them weekly.
Should I temporarily stop the erythropoietin injections due to the retinal vein occlusion, or is it safe to continue? Thank you for taking the time to respond!

Wang, 20~29 year old female. Ask Date: 2022/01/15

Dr. Gao Pilin reply Ophthalmology


Hello Wang: After the fundus photography examination is completed, the physician should arrange the appropriate treatment for you.
If erythropoietin is managed properly, it should not cause venous thromboembolism in patients with anemia, so it is unlikely to be significantly related to retinal vein occlusion.
However, it is still advisable to consult with a nephrologist.

Reply Date: 2022/01/15

More Info


Retinal vein occlusion (RVO) is a significant condition that can lead to various complications, including retinal hemorrhages, vision loss, and other ocular issues. Given your recent diagnosis of left eye retinal vein occlusion leading to retinal bleeding, it is essential to understand the implications of this condition, especially in the context of your existing health issues, such as chronic kidney disease (CKD) and anemia.

RVO occurs when one of the veins carrying blood away from the retina becomes blocked. This blockage can lead to increased pressure in the retinal capillaries, resulting in leakage of fluid and blood into the retina, which can manifest as small black spots in your vision, known as floaters. The severity of the symptoms can vary based on the extent of the blockage and the area of the retina affected.

In your case, the presence of chronic kidney disease and anemia complicates the situation. CKD can lead to changes in blood flow and pressure, potentially exacerbating the risk of vascular occlusions. Anemia, particularly if it is severe, can also affect oxygen delivery to the retina, which may influence the healing process and overall eye health.

Regarding your question about continuing your weekly anemia treatment with erythropoiesis-stimulating agents (ESAs) or iron supplements, it is crucial to consult with your healthcare provider. Generally, the treatment for anemia in patients with CKD is vital for maintaining overall health and can help improve your energy levels and quality of life. However, the specific treatment plan may need to be adjusted based on your current eye condition and any potential risks associated with your treatment.

Here are some considerations:
1. Consult Your Healthcare Provider: It is essential to discuss your retinal vein occlusion with both your nephrologist and your ophthalmologist. They can provide tailored advice based on your overall health status and the severity of your eye condition.

2. Monitoring: Regular follow-up appointments with your eye doctor are crucial. They may recommend imaging tests, such as optical coherence tomography (OCT) or fluorescein angiography, to assess the extent of the blockage and any associated complications.

3. Managing Risk Factors: Since you have chronic kidney disease, managing other risk factors such as blood pressure, blood sugar levels (if diabetic), and cholesterol is vital. These factors can contribute to vascular health and may influence the progression of retinal conditions.

4. Avoiding Strain: While you are managing your eye condition, it may be wise to avoid activities that strain your eyes, such as prolonged screen time or reading in poor lighting conditions. This can help minimize discomfort and potential exacerbation of your symptoms.

5. Emergency Signs: Be aware of any sudden changes in your vision, such as a significant increase in floaters, flashes of light, or a sudden loss of vision. If you experience any of these symptoms, seek immediate medical attention.

In summary, while it is generally important to continue treating anemia, the specifics of your treatment plan should be discussed with your healthcare providers, considering your retinal vein occlusion and chronic kidney disease. They will help you weigh the benefits and risks of continuing your current treatment regimen while ensuring that your eye health is prioritized.

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