PET Scan Results: Is a 1.6cm Liver Nodule Benign? - Internal Medicine

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Inquiry about Positron Emission Tomography (PET) Report


Hello Doctor, I have to wait until Friday to see the report 😭.
I would like to ask if you could confirm my initial translation, which suggests that there is no metastasis or malignant tumor.
Is the 1.6 cm nodule in the liver benign?
1.
There is an approximately 1.6 cm vague hypodense nodule in segment 7 of the liver peripherally, without significantly increased FDG uptake (i.e., lower than or equal to the physiological uptake of the liver).

2.
Otherwise, there is no significant evidence of abnormally increased uptake found throughout the imaged portions of the body, including the neck, lungs, thoracic wall, abdomen, and pelvis, to suggest the presence of FDG-avid metastasis or tumor recurrence in these regions.

3.
There is physiological uptake in the tonsils, salivary glands, myocardium, breasts, liver, spleen, skeletal muscles, bone marrow, and kidneys, with excretion into the ureters, urinary bladder, and bowel.

4.
The accompanying CT shows diffusely low attenuation of the liver.

Impression & suggestion: The scintigraphic findings suggest no significant metabolic evidence of FDG-avid metastasis or tumor recurrence.

Su, 50~59 year old female. Ask Date: 2022/01/22

Dr. Hong Yuanbin reply Internal Medicine


Hello, this report mainly indicates that no signs of tumors or metastasis were found, suggesting that the liver tumor is likely benign.
Thank you for your inquiry.

Reply Date: 2022/01/22

More Info


Based on the information provided in your question regarding the PET scan results, it appears that the 1.6 cm liver nodule in segment 7 (S7) of the liver is likely benign. The key points from your report indicate that the nodule is described as "vague hypodense" and does not show significantly increased uptake of FDG (fluorodeoxyglucose), which is a marker used in PET scans to identify areas of increased metabolic activity typically associated with malignancy.
1. Understanding the Nodule: The fact that the nodule has a lower or equal uptake of FDG compared to the physiological uptake of the liver suggests that it is not exhibiting the characteristics typically associated with malignant tumors. Malignant lesions often show increased FDG uptake due to their higher metabolic activity. Therefore, the absence of significant FDG uptake in your case is a reassuring sign.

2. No Evidence of Metastasis: The report also states that there is no significant evidence of abnormally increased uptake found throughout the imaged portions of the body, including the neck, lungs, thoracic wall, abdomen, and pelvis. This further supports the conclusion that there is no evidence of metastasis or tumor recurrence, which is a positive finding.

3. Physiological Uptake: The report mentions physiological uptake in various organs such as the tonsils, salivary glands, myocardium, breasts, liver, spleen, skeletal muscles, bone marrow, kidneys, and excretions into the urinary system. This is normal and expected in a PET scan, as these areas naturally metabolize glucose.

4. CT Findings: The companion CT scan showing diffusely low attenuation of the liver may indicate conditions such as fatty liver disease or other benign liver conditions. However, it is essential to correlate these findings with clinical history and laboratory results for a comprehensive assessment.

5. Next Steps: While the findings are reassuring, it is crucial to follow up with your healthcare provider for a thorough interpretation of the results in the context of your overall health and any symptoms you may be experiencing. They may recommend monitoring the nodule with follow-up imaging or additional tests to ensure it remains stable over time.

In conclusion, based on the PET scan results you provided, the 1.6 cm liver nodule appears to be benign, and there is no evidence of metastasis or tumor recurrence. However, it is always best to discuss these findings with your physician, who can provide personalized advice and recommendations based on your specific medical history and condition. Regular monitoring and follow-up imaging may be suggested to ensure that the nodule does not change over time.

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