Serotonin syndrome inquiry?
Hello Dr.
Jiang,
I have stopped taking the medication prescribed by the psychiatric clinic (Leeyo) because I need to undergo other related tests at the hospital.
Initially, I was on a low dose (2.5 mg daily for about two weeks).
It has been about a month since I stopped the medication, and I still frequently experience the following symptoms:
1.
My heart rate increases significantly (100-120 bpm) after slight movement or slowly climbing stairs.
2.
Within an hour after sitting down to eat my three meals, my heart rate remains in the 90s.
I researched my symptoms online and found that they resemble serotonin syndrome.
Given the low dosage I was taking, how long should it take for my body to recover after stopping the medication? Is there a way for the hospital to differentiate between panic disorder and serotonin syndrome? Should I consult a neurologist, or is there another specialty I should see? Thank you very much.
Ben, 40~49 year old female. Ask Date: 2022/02/14
Dr. Jiang Junyi reply Neurology
Hello Ben: You mentioned "serotonin storm syndrome," which refers to serotonin syndrome that typically occurs when two or more medications that increase serotonin activity in the brain are combined, potentially leading to the onset of serotonin syndrome.
Recovery usually occurs within 24 hours after discontinuing the medication.
Since you have stopped the medication for over a week, serotonin syndrome should not be a concern.
You noted "a fast heartbeat: 1.
After slight movement or slowly climbing stairs (heart rate 100-120 bpm).
2.
Within an hour after sitting down to eat three meals, the heart rate remains in the 90s." These are all normal physiological responses.
I recommend wearing a smartwatch with blood oxygen monitoring, such as the Apple S6, to track your sleep and blood oxygen levels.
Thank you for your inquiry, and feel free to discuss further! Wishing you good health and peace.
Dr.
Jiang Junyi, Department of Neurology, Taoyuan Hospital, cares about you.
Reply Date: 2022/02/14
More Info
Serotonin syndrome is a potentially life-threatening condition that arises from an excess of serotonin in the brain, often due to the use of certain medications, particularly those that affect serotonin levels. It can occur when medications such as selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and other drugs that increase serotonin are taken together or inappropriately. Symptoms of serotonin syndrome can range from mild to severe and may include agitation, confusion, rapid heart rate, dilated pupils, muscle rigidity, and in severe cases, seizures or loss of consciousness.
In your case, you mentioned that you were taking Leeyo (which is likely a brand name for a medication that affects serotonin levels) at a low dose of 2.5 mg for about two weeks. After discontinuing the medication for a month, you are experiencing symptoms such as a rapid heart rate, especially after physical activity or meals. While it is understandable to be concerned about serotonin syndrome, it is important to note that the symptoms you are experiencing may not necessarily indicate this condition, especially given the low dose and short duration of your medication use.
The symptoms you describe, such as an elevated heart rate after exertion or meals, could be related to several factors, including anxiety, physical deconditioning, or even a response to the cessation of the medication. It is not uncommon for individuals to experience heightened anxiety or physiological responses after stopping a medication that affects mood or anxiety levels. This could lead to symptoms that mimic panic attacks or anxiety disorders.
To address your concerns, it is advisable to consult with a healthcare professional who specializes in mental health, such as a psychiatrist. They can provide a thorough evaluation of your symptoms and determine whether they are indicative of panic disorder, anxiety, or any other condition. A psychiatrist can also assess the possibility of serotonin syndrome, although it is less likely given your medication history.
If you are considering seeing a neurologist, it may not be necessary unless you are experiencing neurological symptoms such as seizures, severe headaches, or other neurological deficits. Your symptoms seem more aligned with anxiety or a physiological response rather than a neurological issue.
In summary, while it is important to be aware of serotonin syndrome, your symptoms may be more related to anxiety or the effects of stopping the medication. A psychiatrist will be best equipped to evaluate your symptoms, provide a diagnosis, and recommend appropriate treatment options. They may also suggest lifestyle modifications, therapy, or alternative medications to help manage your symptoms effectively. Always communicate openly with your healthcare provider about your symptoms and concerns to ensure you receive the best possible care.
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