Stomach Pain: Insights on Medication and Treatment Options - Gastroenterology and Hepatology

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Consultation for Stomach Pain


I have been experiencing stomach pain for the past two weeks, so I visited a gastroenterologist who prescribed Novamin Tablets, which are indicated for the treatment of psychotic disorders, nausea, and vomiting.
However, I do not have these symptoms.
Previously, I had stomach pain for six months without a known cause and was referred to a psychiatrist who diagnosed me with autonomic nervous system dysregulation.
I took Lorazepam for three months, but there was no improvement.
After stopping the medication, I developed insomnia.
I then sought help at a clinic for my insomnia and have been struggling with it for six months, but during the period I was off the controlled medication, my stomach pain surprisingly disappeared, and I have been pain-free for six months.
I am very skeptical about why I was prescribed controlled medication for stomach pain, which has now led to sleep disorders.
During my insomnia treatment, I was prescribed Quetiapine Fumarate for sleep disturbances.
I wonder if the gastroenterologist prescribed Novamin based on my previous medical history or if Novamin can actually treat stomach pain.
I hope the doctor can help me answer this.
Thank you.

Xiao Hao, 30~39 year old female. Ask Date: 2022/02/21

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: Novamin has the following pharmacological effects: 1.
Antiemetic effect: This is produced by inhibiting the chemoreceptor trigger zone in the brain.
2.
Antipsychotic effect: It is generally believed to improve psychotic states by blocking dopamine receptors in the brain.
It is commonly used in gastroenterology for nausea and vomiting, and is not limited to schizophrenia.
Insomnia after discontinuing lorazepam may also be related to the saturation of drug-receptor binding in the body, which can improve after a period of withdrawal.
If insomnia persists, medication adjustments can be made by a psychiatrist.
Changhua Hospital cares about your health.
Dr.
Tsai An-shun.

Reply Date: 2022/02/21

More Info


Understanding stomach pain can be complex, especially when it involves multiple symptoms and potential underlying conditions. Based on your description, it seems you have been experiencing stomach pain for an extended period, and despite various treatments, the pain persisted until you stopped taking certain medications. This situation raises several important points regarding the relationship between gastrointestinal symptoms, medication, and overall health.

Firstly, it’s essential to understand that stomach pain can arise from various causes, including gastritis, ulcers, functional dyspepsia, and even psychosomatic disorders. In your case, the initial diagnosis of autonomic nervous system dysregulation suggests that stress or anxiety could be contributing factors to your gastrointestinal symptoms. Stress can lead to increased gastric acid production, altered gut motility, and heightened sensitivity to pain, which may explain why you experienced stomach pain for so long.

The medication you were prescribed, Novamin (which is often used to treat nausea and vomiting), may not directly address the underlying cause of your stomach pain. Instead, it could have been prescribed based on the assumption that your symptoms were related to nausea or a functional gastrointestinal disorder. However, if you did not experience nausea or vomiting, the effectiveness of this medication for your specific symptoms is questionable.

Lorazepam, a benzodiazepine, is primarily used to treat anxiety and insomnia. While it can help manage anxiety-related symptoms, it may not be the best choice for treating gastrointestinal issues. In fact, some individuals may experience gastrointestinal side effects from benzodiazepines, which could exacerbate stomach pain. The fact that your stomach pain subsided after discontinuing Lorazepam suggests that the medication may have been contributing to your discomfort, possibly through its effects on the gastrointestinal system or through changes in your overall stress levels.

Quetiapine, which you mentioned is being used to address sleep disturbances, is an atypical antipsychotic that can also have sedative effects. While it may help with sleep, it is not typically indicated for gastrointestinal issues. However, if your stomach pain was stress-related, improving your sleep quality could indirectly benefit your gastrointestinal symptoms by reducing overall stress levels.

In terms of treatment options, it is crucial to focus on a holistic approach that addresses both the physical and psychological aspects of your condition. Here are some recommendations:
1. Dietary Modifications: Consider keeping a food diary to identify any potential food triggers that may exacerbate your symptoms. A diet low in irritants (such as caffeine, spicy foods, and alcohol) and high in fiber may help improve gastrointestinal health.

2. Stress Management: Techniques such as mindfulness, cognitive-behavioral therapy (CBT), and relaxation exercises can be beneficial in managing stress and anxiety, which may, in turn, alleviate gastrointestinal symptoms.

3. Regular Follow-ups: Continue to work with your healthcare providers, including both gastroenterologists and mental health professionals, to monitor your symptoms and adjust treatment plans as necessary.

4. Medication Review: Discuss with your doctor the appropriateness of your current medications. If you suspect that certain medications are contributing to your symptoms, it’s essential to have an open dialogue about alternative options.

5. Further Investigations: If symptoms persist or worsen, consider requesting further diagnostic tests, such as an upper endoscopy, to rule out any structural abnormalities or conditions that may require specific treatment.

In conclusion, while medications can play a role in managing stomach pain, it is essential to consider the broader context of your health, including psychological factors and lifestyle choices. A comprehensive approach that includes dietary changes, stress management, and regular medical follow-up is likely to yield the best results in managing your symptoms effectively.

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