Macular Fold in High Myopia: Risks, Treatments, and Management - Ophthalmology

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High myopia and macular folds?


Dr.
Gao, Jun-An has high myopia (right eye -1800 degrees, left eye -1350 degrees), with visual acuity of 0.6 and 0.7.
In October 2021, the doctor informed him of a macular fold, with a thickness of approximately 2671 micrometers.
I would like to ask the doctor the following questions:
1.
Can macular folds occur in one eye or both eyes?
2.
A doctor mentioned that with the current visual acuity, we can continue to observe.
Will the macular fold continue to thicken? Are there any methods to slow down its thickening (such as taking lutein, reducing screen time, limiting computer use, watching less TV, or using smartphones less)? What lifestyle changes can help mitigate its deterioration?
3.
Under what circumstances, such as the thickness of the macular fold or the severity of vision loss, is surgery necessary? If surgery is not performed, is there a risk of blindness?
4.
Given the high myopia, would surgery be a better option compared to not having surgery? Is surgery considered a more favorable treatment approach?
5.
I have been using a sustained-release eye drop for my high myopia for over 20 years.
Could the macular fold potentially be a side effect of this medication?
6.
Is the macular fold classified as dry or wet age-related macular degeneration? Besides surgery, is there an option for injection treatment?
7.
If the surgery does not yield ideal results, could it lead to blindness or further deterioration of vision?
I sincerely request your guidance and advice.
Thank you very much!

AA, 60~69 year old female. Ask Date: 2022/03/17

Dr. Gao Pilin reply Ophthalmology


Hello AA: 1.
It can occur in one eye or both eyes.
2.
There is no particularly effective method to slow it down.
However, you can refer to this: https://bit.ly/36rtXEV.
3.
Without surgery, vision will deteriorate because of macular folds; surgery is only considered if vision declines to a certain extent, based on the physician's judgment.
If vision is still good, surgery may not necessarily improve it.
4.
The decision should be based on the degree of vision deterioration and the expected improvement after surgery.
5.
It should not be.
6.
Neither of those.
7.
This is also a possibility.
Therefore, if vision is still good, it is advisable to monitor the situation.
Please refer to: https://bit.ly/3ibPp3H.

Reply Date: 2022/03/17

More Info


Macular folds, particularly in individuals with high myopia, can be a significant concern due to the potential impact on vision. High myopia, defined as a refractive error greater than -6.00 diopters, is associated with various ocular complications, including retinal detachment, macular degeneration, and the development of macular folds. Understanding the nature of these folds, their risks, and management strategies is crucial for patients experiencing this condition.

1. Unilateral vs. Bilateral Macular Folds: Macular folds can occur in one eye (unilateral) or both eyes (bilateral). In high myopia, it is not uncommon for macular changes to manifest in both eyes, but the severity and presence of folds can vary. Regular monitoring by an ophthalmologist is essential to assess the progression of these folds and any associated complications.

2. Monitoring and Thickness of Macular Folds: The thickness of the macular fold, such as the 2671 micrometers you mentioned, can indicate the severity of the condition. While some doctors may suggest observation if vision remains stable, it is essential to understand that macular folds can progress. Factors such as age, the degree of myopia, and overall eye health can influence this progression. To potentially slow down the thickening of macular folds, lifestyle modifications may be beneficial. Reducing screen time (computers, televisions, smartphones) can help alleviate eye strain, and dietary supplements like lutein and zeaxanthin may support retinal health, although their direct impact on macular folds is still under investigation.

3. Surgical Intervention: The decision to proceed with surgery typically depends on the degree of visual impairment and the thickness of the macular fold. If vision deteriorates significantly or if the fold becomes excessively thick, surgical options may be considered. However, it is important to note that not all cases of macular folds lead to blindness. Many patients maintain some level of vision despite the presence of folds. The risk of vision loss from surgery exists, and careful consideration of the potential benefits versus risks is necessary.

4. Surgical Outcomes in High Myopia: For individuals with high myopia, surgical outcomes can vary. While surgery may improve vision in some cases, it is not guaranteed. The complexity of the eye's anatomy in high myopia can complicate surgical procedures, and the potential for complications may be higher. Therefore, a thorough discussion with a retinal specialist is crucial to weigh the risks and benefits of surgical intervention.

5. Medication and Side Effects: The use of medications such as sustained-release eye drops (like the one you mentioned) over an extended period raises concerns about potential side effects. While it is unlikely that these drops directly cause macular folds, they may contribute to other ocular surface issues. It is essential to discuss any long-term medication use with your ophthalmologist to ensure that it is appropriate for your condition.

6. Nature of Macular Folds: Macular folds are generally classified as a form of dry macular degeneration rather than wet. Wet macular degeneration involves the growth of abnormal blood vessels under the retina, leading to leakage and vision loss. While injections (anti-VEGF therapy) are common for wet macular degeneration, they are not typically used for macular folds. Surgical options, such as vitrectomy or membrane peeling, may be considered if the folds significantly affect vision.

7. Risks of Surgery: As with any surgical procedure, there are risks involved, including the possibility of worsening vision or complications that could lead to blindness. It is crucial to have a detailed discussion with your ophthalmologist about the specific risks associated with your case and the likelihood of achieving a favorable outcome.

In conclusion, managing macular folds in high myopia requires a comprehensive approach that includes regular monitoring, lifestyle adjustments, and careful consideration of surgical options. Open communication with your healthcare provider is essential to navigate this complex condition effectively.

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