Uncontrollable Hand and Foot Tremors After Chemotherapy: Causes and Solutions - Neurology

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After chemotherapy, the hands and feet may experience involuntary shaking?


My mother-in-law is 76 years old and has been undergoing immunotherapy and chemotherapy for bile duct cancer for the past three months.
After these treatments, her hands have started to shake involuntarily.
It has been a month since she stopped treatment, and her hands and feet are still shaking involuntarily.
Could this be caused by a potassium deficiency?

Xiao Jie, 50~59 year old female. Ask Date: 2022/03/18

Dr. Jiang Junyi reply Neurology


Hello Ms.
Hsiao-Jie: You mentioned that your mother-in-law has experienced "involuntary shaking of her hands, and even after stopping treatment for a month, her hands and feet still shake involuntarily.
Could this be caused by low potassium levels?" Symptoms of hypokalemia typically include muscle weakness and even tachycardia, but tremors are rarely seen in the elderly population.
If the tremors began in youth, primary essential tremor should be considered, as this condition tends to worsen with age.
Additionally, emotional stress and anxiety can exacerbate the severity of tremors.
A sudden worsening of symptoms may require consideration of other contributing factors, such as electrolyte imbalances, thyroid dysfunction, or even Parkinson's disease.
It is advisable to consult a neurologist for further evaluation and discussion.
Thank you for your inquiry, and feel free to reach out for further discussion.
Wishing you good health, peace, and happiness.
Dr.
Jiang Jun-Yi, Taoyuan Hospital, cares for you.

Reply Date: 2022/03/18

More Info


Uncontrollable hand and foot tremors after chemotherapy can be a distressing side effect for patients undergoing cancer treatment. In your case, your grandmother, who is 76 years old and has been receiving immunotherapy and chemotherapy for bile duct cancer, is experiencing these tremors even a month after stopping treatment. While it is understandable to suspect that low potassium levels (hypokalemia) could be a contributing factor, there are several other potential causes and solutions to consider.

Firstly, tremors can be a common side effect of chemotherapy and immunotherapy. These treatments can affect the nervous system, leading to peripheral neuropathy, which may manifest as tremors, tingling, or numbness in the hands and feet. Chemotherapy agents, particularly those that target rapidly dividing cells, can inadvertently damage healthy nerve cells, resulting in these symptoms. In some cases, the tremors may also be exacerbated by anxiety or stress related to the cancer diagnosis and treatment.

Another potential cause of tremors is electrolyte imbalances, including low potassium levels. However, tremors can also be associated with deficiencies in other electrolytes, such as magnesium or calcium, or even dehydration. It is essential to have a healthcare professional evaluate your grandmother's electrolyte levels through blood tests to determine if this is a contributing factor.

Additionally, certain medications prescribed during cancer treatment can lead to tremors as a side effect. For example, corticosteroids, which are often used to manage inflammation and side effects of chemotherapy, can cause tremors in some patients. If your grandmother is taking any medications, it would be beneficial to review these with her healthcare provider to assess whether they could be contributing to her symptoms.

To address the tremors, several strategies can be considered:
1. Medical Evaluation: It is crucial to consult with her oncologist or primary care physician to evaluate the cause of the tremors. They may recommend blood tests to check for electrolyte imbalances or other underlying issues.

2. Nutritional Support: If low potassium or other electrolyte deficiencies are identified, dietary adjustments or supplements may be necessary. Foods rich in potassium include bananas, oranges, spinach, and potatoes. However, any supplementation should be done under medical supervision.

3. Physical Therapy: Engaging in physical therapy can help improve muscle control and coordination. A physical therapist can design a tailored exercise program to help manage tremors and improve overall mobility.

4. Stress Management: Since anxiety can exacerbate tremors, incorporating stress-reducing techniques such as mindfulness, meditation, or gentle yoga may be beneficial. These practices can help your grandmother feel more relaxed and may reduce the severity of her tremors.

5. Medication Adjustment: If medications are suspected to be the cause of the tremors, her doctor may consider adjusting the dosage or switching to alternative treatments that have fewer side effects.

6. Supportive Care: Occupational therapy may also be helpful in providing strategies to manage daily activities despite the tremors. This can include adaptive devices that make tasks easier and safer.

In conclusion, while uncontrollable hand and foot tremors after chemotherapy can be concerning, it is essential to approach the situation holistically. A thorough evaluation by healthcare professionals, along with supportive measures, can help manage these symptoms effectively. Your grandmother deserves compassionate care and support during this challenging time, and addressing her tremors can significantly improve her quality of life.

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