Interactions Between Emergency Contraceptives and Common Supplements - Pharmacology

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Interactions of Emergency Contraceptive Pills (Plan B)


Hello, I would like to ask if there are any interactions between oral contraceptives and garlic, B vitamins, and probiotics.
I take oral contraceptives and B vitamins, along with probiotics (taking B vitamins and probiotics at the same time) with a 6-hour interval.
Will there be interactions if I take oral contraceptives and garlic at the same time or with a very short interval? If I wait 12 hours to take garlic, will that have any effect? Thank you.

C, 20~29 year old female. Ask Date: 2022/03/22

Dr. Zheng Shuwen reply Pharmacology


Hello, regarding your inquiry, here is the response: Based on database research, there are no interactions between the contraceptive pill "Mirelle" and garlic, B vitamins, or probiotics, so it can be used safely.
Please remember to carefully read the medication label and pay attention to your body's reactions during the medication period.
If you experience any discomfort or have further questions, feel free to consult your physician or pharmacist.
If you have any other questions, you are welcome to call during business hours.
Thank you.
Consultation phone number: 03-3698553.
Business hours: Monday to Tuesday: 08:30 AM - 10:00 PM; Wednesday to Friday: 08:30 AM - 06:00 PM; Saturday: 08:30 AM - 02:00 PM.

Reply Date: 2022/03/22

More Info


When considering the interactions between emergency contraceptives and common supplements such as garlic, B vitamins, and probiotics, it's essential to understand how these substances may affect each other and the efficacy of the contraceptive.

Emergency Contraceptives Overview:
Emergency contraceptives, such as levonorgestrel (Plan B) or ulipristal acetate (Ella), are designed to prevent pregnancy after unprotected intercourse. They work primarily by delaying ovulation, inhibiting fertilization, or preventing implantation of a fertilized egg. The effectiveness of these medications can be influenced by various factors, including the timing of administration and interactions with other substances.

Garlic:
Garlic is often touted for its health benefits, including its potential to boost the immune system and its anti-inflammatory properties. However, garlic can also act as a natural anticoagulant and has been suggested to have some effects on liver enzymes. While there is limited research on garlic's direct interaction with emergency contraceptives, it is generally recommended to avoid taking large amounts of garlic supplements or raw garlic when using hormonal contraceptives. If you take garlic supplements or consume garlic close to the time of taking emergency contraceptives, it is advisable to space them out as much as possible. Taking garlic 12 hours after the emergency contraceptive should minimize any potential interaction.

B Vitamins and Probiotics:
B vitamins are essential for various metabolic processes in the body and are generally considered safe to take alongside emergency contraceptives. Probiotics, which support gut health, also do not have any known negative interactions with emergency contraceptives. Taking B vitamins and probiotics together, as you mentioned, should not affect the efficacy of emergency contraceptives. However, it is always a good practice to maintain a gap of a few hours between taking different supplements and medications to ensure optimal absorption and minimize any potential interactions.

Timing and Administration:
You mentioned that you take B vitamins and probiotics six hours apart from the emergency contraceptive. This timing is generally acceptable and should not interfere with the effectiveness of the contraceptive. As for garlic, if you take it simultaneously with the emergency contraceptive or within a short time frame, it is advisable to monitor how your body responds. If you have taken garlic 12 hours after the emergency contraceptive, this should be safe and unlikely to affect the contraceptive's effectiveness.

Conclusion:
In summary, while there are no significant interactions reported between emergency contraceptives and B vitamins or probiotics, caution is advised with garlic due to its potential effects on liver enzymes and anticoagulation. It is always best to consult with a healthcare provider regarding any supplements you are taking, especially when using hormonal medications. They can provide personalized advice based on your health history and current medications. Always prioritize spacing out the intake of supplements and medications to ensure the best outcomes for your health and contraceptive efficacy.

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