Androgens can lead to acne?
Hello, doctor.
I have been experiencing persistent acne.
In the past, I took oral isotretinoin until I reached the maximum dosage, and my doctor said I could stop the medication.
However, about a year ago, due to stress, I started breaking out again, and it hasn't improved since.
On March 14, I had a blood test at the gynecology department to check for elevated androgen levels.
Yesterday, I received the report, which confirmed that my levels are indeed above the average maximum value of 53; my result was 59.5.
After returning home, I realized that my menstrual cycle might also affect androgen levels.
I typically get my period around the 24th of each month, which means that March 14 could have been the last couple of days of my ovulation period.
However, the gynecologist did not inquire about this and went ahead with the blood draw.
Therefore, I would like to know if elevated androgen levels could be related to the timing of the test, or if it is not significantly relevant since the doctor did not mention it at the time?
Ms. Li, 20~29 year old female. Ask Date: 2022/03/26
Dr. Lin Xinwang reply Obstetrics and Gynecology
Hello Ms.
Li: Androgens in females are secreted in only small amounts by the ovaries, with the majority being converted from precursors in the bloodstream, so it is not related to the timing of blood draw.
Reply Date: 2022/03/26
More Info
Understanding the impact of male hormones on acne in women is a multifaceted issue that involves hormonal balance, skin physiology, and individual health conditions. In your case, the elevated levels of male hormones (androgens) can indeed contribute to acne development, particularly if they are above the normal range for females.
Androgens, such as testosterone, can stimulate sebaceous (oil) glands in the skin, leading to increased oil production. This excess oil can clog pores, creating an environment conducive to acne formation. Additionally, androgens can influence the skin's inflammatory response, further exacerbating acne lesions.
Regarding your concern about the timing of hormone testing in relation to your menstrual cycle, it is indeed relevant. Hormone levels fluctuate throughout the menstrual cycle, and testing at different times can yield varying results. Typically, androgen levels can be higher during the luteal phase of the cycle, which occurs after ovulation and before menstruation. If your blood test was conducted close to ovulation, it might not accurately reflect your baseline androgen levels.
It is also important to consider other factors that could contribute to your acne, such as stress, diet, and skincare products. Stress can lead to hormonal fluctuations that may worsen acne. Additionally, certain dietary choices, particularly those high in refined sugars and dairy, have been linked to acne in some studies.
If your doctor has confirmed elevated androgen levels, it may be beneficial to explore treatment options that target this hormonal imbalance. Common approaches include hormonal contraceptives, which can help regulate hormone levels and reduce acne, and anti-androgens like spironolactone, which can block the effects of androgens on the skin.
In terms of side effects from hormonal treatments, they can vary depending on the specific medication. Common side effects of hormonal contraceptives may include nausea, breast tenderness, and mood changes. Spironolactone can lead to increased urination, dizziness, and potential electrolyte imbalances, so regular monitoring is essential.
For managing acne, topical treatments such as retinoids, benzoyl peroxide, and salicylic acid can be effective. These treatments work by promoting cell turnover, reducing inflammation, and preventing clogged pores. It's crucial to consult with a dermatologist or healthcare provider to develop a comprehensive treatment plan tailored to your specific needs.
In summary, elevated male hormones can significantly impact acne in women, and the timing of hormone testing in relation to the menstrual cycle is important for accurate assessment. A holistic approach that includes hormonal evaluation, lifestyle modifications, and targeted treatments can help manage acne effectively. If you have further questions or concerns, I encourage you to discuss them with your healthcare provider for personalized advice and treatment options.
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