Elevated White Blood Cell Count: Causes and Next Steps - Internal Medicine

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A white blood cell count of 12.7 is considered elevated. It is important to consult with a healthcare professional to determine the underlying cause of the increased white blood cell count. Possible causes may include infections, inflammation, stress


Hello Doctor, I have iron deficiency anemia and have been taking iron supplements as prescribed for the past six months.
I have had two blood tests during this period, and my hemoglobin and other parameters have been within normal ranges.
My white blood cells and platelets are also normal.
However, during my blood test on March 19, my white blood cell count was 12.7, which is above the normal range of 10.8.
On the day of the blood test, I had inflammation and swelling from my wisdom tooth, and there was some pus near the gums around the tooth.
Could this be the reason for the elevated white blood cell count? I do not feel any other discomfort in my body.
I had my wisdom tooth extracted on March 25, and the doctor ordered a DC test for my next blood draw, which I have not had before.
Should I be concerned that this indicates a serious problem? What should I do?

Tammy, 20~29 year old female. Ask Date: 2022/03/26

Dr. Hong Yuanbin reply Internal Medicine


Hello, the gingival inflammation you mentioned can lead to an increase in white blood cell count.
If the teeth have already been extracted, the white blood cell count should decrease.
Regarding the DC you mentioned, it refers to the differential count of white blood cells, which can help in making a preliminary assessment of the cause if the white blood cell count remains elevated.
I recommend not to worry excessively if there are no specific discomforts; just follow up with a blood test next time.
Thank you for your question.

Reply Date: 2022/03/26

More Info


Elevated white blood cell (WBC) counts can be a source of concern for many patients, especially when they are already dealing with other health issues such as iron deficiency anemia. In your case, the WBC count of 12.7 (with a normal range being up to 10.8) is indeed elevated, but it is essential to consider the context in which this elevation occurred.

One of the most common reasons for an elevated WBC count is an infection or inflammation. Since you mentioned that you had an inflamed wisdom tooth at the time of your blood draw, this could very well explain the increase in your WBC count. The body responds to infections by producing more white blood cells, which are crucial for fighting off pathogens. In your case, the localized infection in your mouth likely triggered your immune system to ramp up WBC production, resulting in the elevated count.

It's also worth noting that the body can react to various stressors, including physical stress, emotional stress, or even recent surgical procedures (like your wisdom tooth extraction), which can also lead to temporary increases in WBC counts. After the extraction, your body will continue to heal, and it is common for WBC counts to fluctuate during this recovery period.

Regarding your concern about the next steps, your doctor has advised you to have further blood tests, including a differential count (DC). This test will provide more detailed information about the different types of white blood cells present in your blood. A differential count can help determine whether the elevation in WBCs is due to an increase in neutrophils (often associated with bacterial infections), lymphocytes (often associated with viral infections), or other types of white blood cells. This information can help your healthcare provider understand the underlying cause of the elevated count better.

It is important to follow up with your healthcare provider after your next blood test. If the WBC count returns to normal and you are feeling well, it may simply have been a temporary response to the infection. However, if the count remains elevated or if you develop new symptoms, further investigation may be warranted to rule out other potential causes, such as chronic inflammation or hematological conditions.

In summary, while an elevated WBC count can be alarming, it is often a normal response to infection or inflammation. Your recent dental issue likely contributed to this elevation. Continue to monitor your health, follow your doctor's recommendations for further testing, and maintain open communication with your healthcare provider about any concerns you may have. This proactive approach will help ensure that any potential issues are addressed promptly and appropriately.

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