Managing Medication Withdrawal: Risks and Alternatives for Mental Health - Psychiatry

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Drug withdrawal


I am currently taking Fluoxetine.
Some time ago, I read "Crazy for Drugs." Although the author's views on side effects are somewhat exaggerated, I did experience suicidal thoughts when I took Paroxetine in my youth.
It's been about thirty-five years since I started medication, and my physical condition is generally good, though I do have frequent minor illnesses and a relatively weak constitution.
At sixty years old, I find it quite troublesome, as I tend to focus on health and wellness.
Six months ago, my dosage was reduced to 75 mg per week.

My question is, if I gradually taper off the medication or even stop it altogether, will my body be unable to cope, or will I experience significant withdrawal symptoms? Would practicing Qigong or yoga help reduce the risks? However, continuing to take medication for life might also harm my body or brain function, right? Currently, I am more troubled by excessive sleepiness and gastroesophageal reflux.
Are these related to the medication? Thank you for taking the time to read my letter.

Xiao Xiao, 60~69 year old female. Ask Date: 2022/04/23

Dr. Xue Gengming reply Psychiatry


Regarding issues related to medication reduction, drowsiness, and gastroesophageal reflux, it is advisable for you to discuss these matters further with your attending physician to determine if further examinations or consultations with relevant specialties are necessary.
Thank you, and wishing you good health!

Reply Date: 2022/04/23

More Info


Managing medication withdrawal, especially from antidepressants like Lexapro (escitalopram), can be a complex and challenging process. It's essential to approach this situation with caution and a well-thought-out plan, particularly given your long history of medication use and the potential for withdrawal symptoms.

Firstly, it’s important to understand that long-term use of antidepressants can lead to physical dependence, and abrupt discontinuation can result in withdrawal symptoms. These symptoms can include mood swings, irritability, anxiety, dizziness, flu-like symptoms, and in some cases, a resurgence of depressive symptoms. Therefore, if you are considering tapering off your medication, it is crucial to do so under the guidance of a healthcare professional. A gradual reduction in dosage is typically recommended to minimize withdrawal effects.

You mentioned that you have been on medication for about 35 years, which indicates a significant period of reliance on these drugs. This long-term use can lead to changes in brain chemistry, and stopping the medication suddenly may lead to a rebound effect where symptoms of depression or anxiety return, sometimes more intensely than before. Therefore, a slow and monitored tapering process is advisable.
In terms of your current symptoms of excessive sleepiness and gastroesophageal reflux disease (GERD), these could indeed be related to your medication. Antidepressants can have side effects that impact sleep patterns and gastrointestinal function. For example, some individuals experience sedation as a side effect, which could explain your excessive sleepiness. GERD can also be exacerbated by certain medications, particularly those that relax the lower esophageal sphincter. It would be beneficial to discuss these symptoms with your healthcare provider, as they may need to adjust your treatment plan accordingly.

Incorporating practices such as yoga and qigong can be beneficial for managing stress and improving overall well-being. These practices can enhance mindfulness, reduce anxiety, and promote relaxation, which may help mitigate some withdrawal symptoms. However, they should not be seen as a replacement for medical treatment but rather as complementary approaches.
It's also worth noting that while the idea of lifelong medication can be daunting, it is essential to weigh the benefits against the potential risks. Some individuals find that they can successfully taper off their medications and manage their mental health through lifestyle changes, therapy, and alternative treatments. Others may find that they need to remain on medication to maintain their mental health stability.
Ultimately, the decision to continue or discontinue medication should be made collaboratively with your healthcare provider, considering your unique circumstances, medical history, and current health status. Regular follow-ups and open communication with your doctor will be crucial during this process. They can provide support, monitor your progress, and adjust your treatment plan as necessary to ensure that you are managing your mental health effectively while minimizing any potential risks associated with withdrawal.
In conclusion, managing medication withdrawal requires careful planning and professional guidance. While lifestyle changes like yoga and qigong can support your mental health, they should be part of a comprehensive approach that includes medical oversight. Always consult with your healthcare provider before making any changes to your medication regimen.

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