Managing Panic Disorder: Medication Challenges and Recovery Insights - Psychiatry

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Medications for Panic Disorder Relapse


I reduced my medication dosage to half a pill before the New Year and felt better, so I stopped taking the medication.
However, in April after the New Year, I started experiencing a relapse of autonomic nervous system symptoms, accompanied by increasingly frequent panic attacks.
The tremors have become quite severe.
Therefore, I switched to another psychiatrist who prescribed one pill of Prozac at 4 PM to help with my symptoms, along with one pill of Seroquel at bedtime to reduce appetite.
After taking one pill of Ativan for just three days, I felt extremely dizzy, weak, and fatigued.
Is this normal? If I reduce it to half a pill, I want to avoid feeling so drowsy, but I start to tremble again and experience some palpitations.
I have to wait four more days to discuss this with my doctor, and I want to understand why panic attacks are so difficult to resolve.
After two years of medication, I feel somewhat disillusioned.

Xu Xiaoqian, 30~39 year old female. Ask Date: 2022/05/07

Dr. Wang Yaoting reply Psychiatry


Hello: I'm not sure if the medication you mentioned, "reducing half a pill," refers to Escitalopram? Since you are taking two serotonin medications (Prozac and Escitalopram), if you experience any discomfort, it is advisable to keep only one of them and temporarily stop the newly added medication.
In fact, medication treatment is usually aimed at managing acute panic symptoms and accompanying autonomic nervous system dysregulation.
To prevent relapse after stopping medication, it is important to make significant lifestyle changes, reduce sources of stress, find a focus in life, and maintain a regular routine and sleep schedule.
In addition to discussing treatment options with your physician, you may also consider arranging for blood tests to check for any underlying medical conditions that could trigger panic (e.g., thyroid dysfunction), and ruling out these potential factors.
Additionally, you might consider seeking psychological therapy.
I hope this answers your question :)

Reply Date: 2022/05/07

More Info


Managing panic disorder can be a complex and challenging journey, especially when it comes to medication management and the psychological aspects of recovery. Your experience of reducing medication and subsequently experiencing a resurgence of panic symptoms is not uncommon. Many individuals with panic disorder face similar challenges, and understanding the underlying mechanisms can help in navigating this difficult path.

Firstly, it’s important to recognize that panic disorder is often characterized by recurrent and unexpected panic attacks, which can lead to significant anxiety about future attacks. This cycle can create a heightened state of vigilance and fear, making it difficult to manage symptoms effectively. When you reduced your medication, it’s possible that your body experienced withdrawal symptoms or a resurgence of anxiety, which can trigger panic attacks. This is particularly true if the medication was helping to stabilize your mood and anxiety levels.

The medications you mentioned—such as Prozac (fluoxetine), which is an SSRI (selective serotonin reuptake inhibitor), and Effexor (venlafaxine), which is an SNRI (serotonin-norepinephrine reuptake inhibitor)—are commonly prescribed for anxiety and panic disorders. These medications work by increasing the levels of serotonin and norepinephrine in the brain, which can help improve mood and reduce anxiety. However, they can also have side effects, especially when starting or adjusting dosages. The feelings of dizziness, fatigue, and general malaise you described could be side effects of the medication, particularly if your body is adjusting to a new dosage or if the medication is not the right fit for you.

It’s crucial to communicate openly with your healthcare provider about your symptoms and side effects. If you are feeling excessively tired or experiencing tremors, these are important signals that should be addressed. Your doctor may need to adjust your medication regimen, either by changing the dosage or switching to a different medication that may be better tolerated. It’s also worth noting that finding the right medication can take time, and it often requires a process of trial and error.

In addition to medication, incorporating therapeutic approaches such as cognitive-behavioral therapy (CBT) can be highly beneficial for managing panic disorder. CBT helps individuals identify and challenge negative thought patterns and develop coping strategies to manage anxiety and panic symptoms. Mindfulness and relaxation techniques, such as deep breathing exercises, progressive muscle relaxation, and guided imagery, can also be effective in reducing anxiety and preventing panic attacks.

Moreover, lifestyle factors play a significant role in managing panic disorder. Regular physical activity, a balanced diet, adequate sleep, and avoiding stimulants (such as caffeine and nicotine) can help stabilize mood and reduce anxiety levels. Engaging in social support, whether through friends, family, or support groups, can also provide emotional relief and reduce feelings of isolation.

Lastly, it’s essential to be patient with yourself during this process. Recovery from panic disorder is often not linear, and setbacks can occur. However, with the right support, treatment, and coping strategies, it is possible to manage symptoms effectively and improve your quality of life. If you find that your current treatment plan is not working, don’t hesitate to seek a second opinion or explore additional resources, such as therapy or support groups, to aid in your recovery journey. Remember, you are not alone in this, and there are many avenues available to help you regain control over your life.

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