Do Skincare Products with Kojic Acid Increase Cancer Risk? - Dermatology

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Does using products containing kojic acid cause cancer?


Hello Dr.
Zheng, I recently saw a news report on television stating that Japanese skincare products containing kojic acid may be carcinogenic, but it did not provide detailed information about which specific products or brands were involved, just glossed over the topic.
I don't have a habit of using skincare products, but since I often work outdoors, I do use sunscreen products, and I usually prefer Japanese brands.
I would like to know if sunscreen products can also be carcinogenic.
Is there a problem with just applying it to my face and skin? The news report mentioned that skincare products containing kojic acid may be carcinogenic; does this include sunscreen products? Generally, these are applied to the skin's surface and are not ingested.
What type of cancer was the news referring to? I look forward to your response.
Sincerely, Xiao Bin.

Xiao Bin, 20~29 year old female. Ask Date: 2003/08/19

Dr. Zheng Lizhen reply Dermatology


Hello! The conclusions of this experiment are based on feeding animals with kojic acid, not on topical application to the skin.
Therefore, the claims regarding its carcinogenicity are still controversial.
Currently, only the Ministry of Health, Labour and Welfare in Japan has banned skincare products containing kojic acid, while no similar actions have been taken in other regions.
Kojic acid is primarily used in skincare products that claim to have whitening effects, but not every whitening product or brand contains this ingredient.
It is advisable to carefully read the product ingredient descriptions before use.
Best wishes for health from Dr.
Cheng Li-Chen, Dermatology Department, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2003/08/19

More Info


The concern regarding the potential carcinogenic effects of kojic acid in skincare products, particularly those from Japan, has gained attention in recent media reports. Kojic acid is commonly used in various cosmetic formulations, especially those aimed at skin whitening. However, the assertion that it poses a cancer risk is not straightforward and requires a nuanced understanding.

Firstly, the studies that have raised alarms about kojic acid primarily involve animal models where the substance was administered orally in high doses. These studies have not conclusively demonstrated that topical application of kojic acid leads to cancer in humans. The Japanese Ministry of Health has taken a precautionary approach by banning kojic acid in certain skincare products, but this decision is not universally adopted, and many countries continue to allow its use in cosmetics. The lack of widespread regulatory action suggests that the evidence linking kojic acid to cancer remains inconclusive.

Regarding your specific question about sunscreen products, it is essential to clarify that most sunscreens do not typically contain kojic acid. Sunscreens are formulated to protect the skin from harmful ultraviolet (UV) radiation, which is a well-established risk factor for skin cancer. The primary ingredients in sunscreens are designed to absorb or reflect UV rays, and while some may contain additional components for skin benefits, kojic acid is not a standard ingredient in these formulations.

When applying any skincare product, including sunscreens, the risk of systemic absorption is generally low. The skin acts as a barrier, and while some ingredients can penetrate the skin, the concentration and type of substance play significant roles in determining any potential risk. The mere act of applying a product to the skin does not equate to ingestion, and thus the cancer risk associated with oral consumption does not directly translate to topical use.

It is also worth noting that the media often sensationalizes health risks without providing comprehensive context. The specific types of cancer that might be associated with kojic acid exposure, if any, have not been clearly defined in the reports. Therefore, it is crucial to approach such claims with a critical eye and rely on scientific evidence rather than anecdotal reports.

For individuals who spend considerable time outdoors, using a broad-spectrum sunscreen with an SPF of 30 or higher is recommended to protect against UV radiation. The Cancer Council recommends SPF 50+ for those with prolonged sun exposure, as it provides better protection against UVB rays, which are primarily responsible for sunburn and skin cancer.

In conclusion, while the concerns regarding kojic acid in skincare products are valid and warrant attention, the current evidence does not support a definitive link to cancer risk from topical application. Sunscreens, which are essential for protecting against UV radiation, do not typically contain kojic acid and are crucial for skin health, especially for those engaged in outdoor activities. It is always advisable to read product labels carefully and consult with a dermatologist if you have specific concerns about the ingredients in your skincare routine.

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