Depression upon palpation of the muscles above the tibia in the lower leg?
Hello Dr.
Wu, I apologize for bothering you, but I would like to ask you a question.
Recently, I suddenly noticed that when I press on the muscles around my tibia in both calves, they indent and do not bounce back, while other areas of my calves, including my ankles and the soles of my feet, do not have this issue.
Only the area around the tibia indents when pressed, and it feels somewhat like pressing on harder soil, requiring a certain amount of pressure to indent.
I have stage 2 kidney disease, and here are the results from my blood test last Saturday:
- Urine Creatinine: 123.0 mg/dL
- Urine Protein: 69.9 * mg/dL < 14
- Protein/(Creatinine/1000): 568.29 mg/g
- B.U.N: 19 mg/dL (5-26)
- Creatinine: 1.13 mg/dL (Male: 0.6-1.3; Female: 0.4-1.1)
- GFR: 71 mL/min/1.73㎡
- Albumin: 4.4 g/dL (3.8-5.3)
- Globulin: 2.8 g/dL (2.5-3.6)
- Calcium (Ca): 9.2 mg/dL (8.6-10.3)
- Phosphorus (P): 3.8 mg/dL (2.7-4.5)
- Sodium (Na): 139 mmol/L (135-147)
- Potassium (K): 4.4 mmol/L (3.5-4.9)
- Glucose A.C.: 101 mg/dL (70-100)
- HbA1c: 6.2 * % (4-6)
- Sugar: Negative mg/dL ≦50 (- ~ ±)
- Bilirubin: Negative (-)
- Ketone: Negative (-)
- Specific Gravity: 1.020 (1.003-1.035)
- Occult Blood: ± (- ~ ±)
- pH: 6.0 (5.0-8.0)
- Protein: 70 mg/dL (≦20)
- Urobilinogen: <1.5 EU/dL (<1.5)
- Nitrite: Negative (-)
- Leukocyte: - (- ~ ±)
- Appearance: Color: YELLOW
Microscopic Exam:
- RBC: 1-2 /HPF (0-2)
- WBC: 0-1 /HPF (0-6)
- Epith Cell: 0-1 /HPF (0-5)
- Cast: - /LPF
- Crystal: - /HPF
- Bacteria: - /HPF
I have heard that if there is edema in the lower limbs, it indicates that kidney damage is already quite severe.
Additionally, I have hypertension that has been well-controlled, but my diastolic pressure tends to be higher (for example, sometimes the ratio of systolic to diastolic pressure is such that the diastolic pressure is significantly higher, like 105/85).
Thank you, Dr.
Wu.
Xiao Min, 40~49 year old female. Ask Date: 2022/05/24
Dr. Wu Jiyu reply Internal Medicine
According to your inquiry, the report you provided shows that urine protein levels are at 568 mg/g, which exceeds the normal value (<150 mg/g).
This may require a discussion with a nephrologist regarding treatment options and adherence to a low-protein diet.
Regarding the indentation observed upon pressing the muscles above the tibia, it cannot be definitively determined as edema, and it may sometimes be associated with certain blood pressure medications.
This also needs to be discussed with your physician.
Thank you for your inquiry.
The Nephrology Department at Changhua Hospital is concerned about your health.
Reply Date: 2022/05/24
More Info
Understanding muscle indentation above the tibia, particularly in the context of kidney health, requires a comprehensive evaluation of various factors, including kidney function, hydration status, and potential underlying conditions. Your concern regarding the indentation observed when pressing on the muscles above the tibia, alongside your existing diagnosis of stage 2 chronic kidney disease (CKD), is indeed significant and warrants careful consideration.
Firstly, the indentation you are experiencing could be related to several factors. In individuals with kidney disease, fluid retention and changes in muscle tone can occur due to electrolyte imbalances or altered fluid distribution. The fact that you notice this indentation specifically above the tibia suggests localized muscle or tissue changes, which could be due to muscle atrophy or edema. In CKD, muscle wasting is not uncommon, and it can be exacerbated by factors such as dietary restrictions, reduced physical activity, or metabolic changes associated with kidney dysfunction.
Your recent lab results indicate that your urine protein level is elevated at 69.9 mg/dL, which is significantly above the normal range (<14 mg/dL). This proteinuria can be a marker of kidney damage and may contribute to the symptoms you are experiencing. The presence of protein in the urine is often associated with glomerular damage, which can lead to further complications if not managed appropriately. Additionally, your creatinine level of 1.13 mg/dL and GFR of 71 mL/min suggest that your kidney function is moderately impaired, which aligns with your diagnosis of stage 2 CKD.
The concern about lower limb edema, which you mentioned, is indeed a common sign of worsening kidney function. However, it is important to note that not all patients with CKD will experience edema, and its absence does not necessarily indicate stable kidney function. The indentation you are observing may not directly correlate with fluid retention but could reflect changes in muscle composition or tone due to your kidney condition.
Regarding your blood pressure, it is crucial to maintain it within a healthy range, especially in the context of CKD. Elevated diastolic pressure, as you described, can be concerning and may require further evaluation and management. High blood pressure can exacerbate kidney damage, so it is essential to work closely with your healthcare provider to optimize your blood pressure control.
In terms of dietary considerations, individuals with CKD often need to modify their protein intake, sodium, and potassium levels to prevent further kidney damage and manage symptoms. Consulting with a renal dietitian can provide personalized guidance on how to adjust your diet to support your kidney health while addressing any nutritional deficiencies that may arise from dietary restrictions.
Lastly, it is advisable to have regular follow-ups with your nephrologist to monitor your kidney function and any changes in your symptoms. If you notice any worsening of your condition, such as increased swelling, changes in urine output, or new symptoms, it is important to seek medical attention promptly.
In summary, the indentation above your tibia may be related to muscle changes associated with your kidney disease, and your elevated protein levels indicate a need for careful monitoring and management of your kidney health. Regular follow-ups, dietary adjustments, and blood pressure management are essential components of your care plan. If you have further concerns or notice any new symptoms, do not hesitate to reach out to your healthcare provider for a thorough evaluation.
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