Persistent Low-Grade Fever in COVID-19 Patients - Internal Medicine

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Regarding the persistent low-grade fever in confirmed cases of COVID-19?


Hello: I tested positive for COVID-19 via PCR on May 12.
From May 11 to May 14, my axillary temperature was 37.5 degrees Celsius.
From May 15 to May 24, my daily axillary temperature ranged from 37 to 37.3 degrees Celsius.
Currently, I am experiencing a persistent low-grade fever and a slight discomfort, but I can still engage in normal activities and eat and drink without any other symptoms.
Is this persistent low-grade fever normal? Under what circumstances should I seek consultation with an infectious disease specialist? Thank you!

Xinni, 30~39 year old female. Ask Date: 2022/05/24

Dr. Hong Yuanbin reply Internal Medicine


Hello, if you experience moderate to severe symptoms such as shortness of breath, chest pain, or altered consciousness, you should seek medical attention.
If these symptoms are not present, it is advisable to rest more and drink plenty of water, as you should gradually improve.
Thank you for your question.

Reply Date: 2022/05/24

More Info


Persistent low-grade fever in COVID-19 patients can be a concerning symptom, especially for those who have recently tested positive for the virus. In your case, having a consistent temperature between 37.0°C and 37.3°C following your COVID-19 diagnosis is not uncommon. Many patients experience a range of symptoms during and after their infection, and low-grade fever can be one of them.


Understanding Persistent Low-Grade Fever
1. Definition and Normalcy: A low-grade fever is typically defined as a body temperature that is slightly elevated, generally between 37.1°C and 38.0°C. In the context of COVID-19, it can be a sign of the body’s immune response to the virus. Your body is working to fight off the infection, which can manifest as a mild fever.
2. Duration: It is important to note that fevers can persist for several days or even weeks after the initial infection, particularly in cases of viral illnesses like COVID-19. This phenomenon is often referred to as "post-viral syndrome" or "long COVID," where symptoms linger even after the acute phase of the illness has resolved.

3. Symptoms to Monitor: While a persistent low-grade fever can be normal, it is essential to monitor for any changes in your condition. If you start to experience additional symptoms such as:
- Increased fever (above 38°C)
- Severe fatigue
- Shortness of breath
- Chest pain
- New or worsening cough
- Confusion or difficulty waking
- Any other unusual symptoms
It would be advisable to seek medical attention. These could indicate a secondary infection or complications related to COVID-19.


When to Seek Medical Attention
You should consider consulting an infectious disease specialist or your primary care physician if:
- Your fever persists beyond two weeks without improvement.

- You experience any of the concerning symptoms mentioned above.

- You have underlying health conditions that may complicate your recovery.

- You feel increasingly unwell or unable to perform daily activities.


Additional Considerations
1. Post-COVID Care: After recovering from COVID-19, some individuals may experience lingering symptoms, including fatigue, brain fog, and low-grade fever. This is part of the broader spectrum of post-COVID conditions, which can affect anyone who has had the virus, regardless of the severity of their initial illness.

2. Monitoring and Testing: If your symptoms persist or worsen, your healthcare provider may recommend further testing to rule out other infections or complications. This could include blood tests, imaging studies, or additional PCR tests to check for viral load.

3. Self-Care: In the meantime, ensure you are taking care of your overall health. Stay hydrated, rest adequately, and maintain a balanced diet to support your immune system. Over-the-counter medications like acetaminophen or ibuprofen can help manage fever and discomfort, but consult with your healthcare provider before starting any new medication.

4. Mental Health: The uncertainty and anxiety surrounding COVID-19 can also impact your mental health. If you find yourself feeling anxious or stressed about your symptoms, consider discussing this with a healthcare professional who can provide support or resources.

In summary, while a persistent low-grade fever can be a normal part of recovery from COVID-19, it is crucial to remain vigilant and seek medical advice if your condition changes or if you have any concerns. Your health and well-being should always be your top priority.

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