Can You Safely Use Birth Control While Taking Antibiotics? - Obstetrics and Gynecology

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The use of antibiotics coincides with the administration of contraceptive pills?


Hello, Doctor: I started taking Monke Apricot Tablets for urethritis on May 27, but I finished my first pack of PrEP (Truvada) on May 25.
Although the doctor who prescribed the antibiotics said it was okay to continue PrEP, I would like to ask if it is safe to have unprotected sex during this time.
If not, should I wait a few days after finishing the antibiotics before starting again?

Niming, 20~29 year old female. Ask Date: 2022/05/27

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, the two do not interfere with each other; as long as you are taking contraceptive pills, there will be contraceptive effectiveness.
Wishing you good health.

Reply Date: 2022/05/27

More Info


When it comes to the use of birth control while taking antibiotics, there are several important considerations to keep in mind. The primary concern revolves around whether antibiotics can interfere with the effectiveness of hormonal contraceptives, such as birth control pills.

Historically, it was believed that certain antibiotics could reduce the effectiveness of birth control pills, leading to unintended pregnancies. However, current medical guidelines indicate that most antibiotics do not have a significant impact on the efficacy of hormonal contraceptives. The most notable exception is rifampin, an antibiotic used to treat tuberculosis, which has been shown to decrease the effectiveness of hormonal birth control methods. For most other antibiotics, including those commonly prescribed for urinary tract infections, such as the one you mentioned (likely referring to a type of antibiotic like nitrofurantoin or trimethoprim-sulfamethoxazole), there is no substantial evidence to suggest that they interfere with the effectiveness of birth control pills.

Given this information, if you are taking a standard antibiotic for a urinary tract infection, it is generally considered safe to continue having unprotected sex while on hormonal birth control. However, it is always prudent to consult with your healthcare provider for personalized advice, especially if you have any concerns or if you are taking a specific antibiotic that may have different interactions.

In terms of timing, if you have been taking your birth control pills consistently and correctly, you should remain protected against pregnancy, even while on antibiotics. However, if you missed any doses of your birth control pill or if you have been taking the antibiotic for an extended period, it may be wise to use a backup method of contraception, such as condoms, until you have completed the course of antibiotics and have taken your birth control pills consistently for at least seven days.

Additionally, it is important to consider that while antibiotics may not affect hormonal birth control, they can have other side effects that might impact your overall health and well-being. For instance, antibiotics can disrupt the natural balance of bacteria in your body, potentially leading to yeast infections, which can also affect sexual health. If you experience any unusual symptoms or side effects while taking antibiotics, it is advisable to reach out to your healthcare provider for further evaluation.

In summary, while most antibiotics do not interfere with the effectiveness of hormonal birth control, it is essential to maintain consistent use of your contraceptive method and consult with your healthcare provider for personalized guidance. If you have any doubts or if you are taking a specific antibiotic that may have different implications, using a backup method of contraception is a prudent approach until you can confirm your safety with your healthcare provider.

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