Luteal Phase Decline: Symptoms and Diagnosis in Women's Health - Obstetrics and Gynecology

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Decline in progesterone levels?


Hello Dr.
Wei: Recently, my friend visited a gynecologist for an internal examination, and the doctor informed her that her uterus showed signs of atrophy, indicating a decrease in progesterone levels.
This condition can lead to frequent lower back pain and may reduce the chances of pregnancy.
I am concerned that I might be experiencing the same issue, so I consulted another gynecologist.
She stated that an internal examination cannot determine this condition and that a blood test is necessary.
I would like to ask you which doctor is correct.
Can such symptoms truly be identified through an internal examination? Additionally, I previously underwent a hysterosalpingography due to infertility, and since then, I have noticed intermittent pain on the right side.
Another doctor mentioned there is slight swelling, but it has been six months since the examination.
Could this pain be a result of the procedure? I have never experienced this before.
Thank you for your thoughtful response.

qq, 30~39 year old female. Ask Date: 2003/08/22

Dr. Wei Fumao reply Obstetrics and Gynecology


To confirm progesterone deficiency, it is necessary to measure basal body temperature or conduct a blood test.
I apologize for being unable to answer the second question.

Reply Date: 2003/08/22

More Info


Understanding the luteal phase decline and its implications for women's health is essential, especially as it relates to fertility and overall reproductive health. The luteal phase is the second half of the menstrual cycle, occurring after ovulation and before the onset of menstruation. During this phase, the hormone progesterone rises, preparing the uterine lining for a potential pregnancy. If pregnancy does not occur, progesterone levels decline, leading to menstruation.

In your friend's case, the physician's observation of uterine atrophy suggests that there may be a decrease in hormone levels, particularly progesterone. Uterine atrophy can occur due to various factors, including hormonal imbalances, age, and certain medical conditions. Symptoms such as lower back pain can indeed be associated with hormonal fluctuations, as they can affect the pelvic region and overall comfort.

However, the second physician's assertion that a blood test is necessary for a definitive diagnosis is also valid. While a pelvic examination can provide some insights into the physical state of the uterus and ovaries, it cannot accurately measure hormone levels. Blood tests, particularly those measuring progesterone, estrogen, and other relevant hormones, are crucial for diagnosing hormonal imbalances and understanding the luteal phase's status.

Regarding the pain your friend is experiencing on the right side after undergoing a hysterosalpingogram (HSG) — a procedure used to examine the fallopian tubes and uterine cavity — it is not uncommon for women to experience discomfort following this test. The procedure can sometimes cause temporary inflammation or irritation in the pelvic area, leading to pain. However, if the pain persists or worsens, it is essential to consult a healthcare provider to rule out any complications, such as an infection or other underlying conditions.

In summary, both physicians have valid points. A pelvic examination can provide some information, but blood tests are necessary for a comprehensive understanding of hormonal levels and reproductive health. If there are ongoing symptoms or concerns about fertility, it is advisable to seek further evaluation from a healthcare provider specializing in reproductive endocrinology or gynecology. They can provide a thorough assessment and recommend appropriate treatment options based on the findings.

In addition, it is crucial to consider lifestyle factors that may influence hormonal health, such as diet, exercise, stress management, and sleep quality. These factors can significantly impact hormonal balance and overall well-being. If your friend is concerned about her reproductive health or experiencing symptoms related to hormonal changes, she should not hesitate to seek further evaluation and support from healthcare professionals. Regular check-ups and open communication with healthcare providers can help manage symptoms and maintain reproductive health effectively.

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