Is It Ulcerative Colitis? Acute Colitis Symptoms and Diagnosis - Surgery

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Ulcerative Colitis


Doctor, I started experiencing abdominal pain, diarrhea with blood and mucus symptoms (4-5 times a day) in early May.
After seeking medical attention, I underwent a colonoscopy and biopsy.
The colonoscopy revealed multiple diffuse ulcerations in the colon, but the biopsy samples (five sites) indicated acute enteritis rather than chronic conditions.
All other blood test results, including CBC, CRP, and ANA, were normal, and the amoebic antibody test was negative.
Does this diagnosis qualify as ulcerative colitis? The physician believes it is acute enteritis based on the pathology and blood reports, and I am currently receiving conservative treatment.
My symptoms have improved somewhat, with a slight reduction in abdominal pain, diarrhea, and blood in the stool, but I still have the following related reports: https://ppt.cc/ftHuyx https://ppt.cc/fyLdOx https://ppt.cc/fJff5x https://ppt.cc/fkfiqx https://ppt.cc/flA2rx

Guang, 40~49 year old female. Ask Date: 2022/06/01

Dr. Zhang Shuhao reply Surgery


During inflammation of the intestinal mucosa, it is difficult to differentiate between acute and chronic conditions based on clinical symptoms and colonoscopy findings.
Therefore, confirming a diagnosis of Ulcerative Colitis relies on the pathology report, which in this case does not provide strong evidence to confirm Ulcerative Colitis.
Furthermore, acute enteritis can improve with general conservative treatment, including electrolyte replacement and a bland diet, while Ulcerative Colitis requires anti-inflammatory medications for significant improvement.
It is recommended to follow up with a colonoscopy in three to six months.

Reply Date: 2022/06/01

More Info


Based on the information provided, it appears that you are experiencing symptoms that could be indicative of ulcerative colitis (UC), but the current diagnosis leans towards acute colitis rather than chronic inflammatory bowel disease. Let’s break down the details to better understand your situation.


Symptoms and Initial Findings
You mentioned experiencing abdominal pain, diarrhea, and blood and mucus in your stool, with a frequency of 4-5 times a day. These symptoms are common in various forms of colitis, including ulcerative colitis and infectious colitis. The presence of multiple ulcers in the colon observed during the colonoscopy is significant, as it suggests inflammation and damage to the colonic mucosa.


Diagnostic Approach
The diagnosis of ulcerative colitis typically requires a combination of clinical symptoms, endoscopic findings, and histological examination of biopsy samples. In your case, the colonoscopy revealed diffuse ulcerations, which is a concerning sign. However, the biopsy results indicated acute inflammation rather than chronic changes typically associated with ulcerative colitis.
Acute colitis can be caused by a variety of factors, including infections (bacterial, viral, or parasitic), ischemia, or even medication side effects. The negative results for amoebic antibodies and normal blood tests (CBC, CRP, ANA) further support the idea that this may not be a chronic condition like ulcerative colitis.


Distinguishing Between Acute Colitis and Ulcerative Colitis
1. Duration and Pattern of Symptoms: Ulcerative colitis is a chronic condition characterized by periods of flare-ups and remission. If your symptoms have been persistent and are improving with treatment, it may suggest a less chronic process.


2. Histological Findings: The biopsy results showing acute inflammation without chronic changes (like crypt distortion or basal plasmacytosis) are more indicative of acute colitis rather than ulcerative colitis.
3. Response to Treatment: The fact that your symptoms are improving with conservative treatment is a positive sign. In ulcerative colitis, symptoms may not improve as quickly without specific medications like 5-ASA compounds or corticosteroids.


Recommendations
1. Continued Monitoring: Since your symptoms are improving, it’s essential to continue monitoring your condition. Regular follow-ups with your gastroenterologist are crucial to assess the healing of the colon and to determine if further intervention is needed.

2. Repeat Endoscopy: If symptoms persist or worsen, a repeat colonoscopy may be warranted to reassess the mucosal condition and to rule out any underlying chronic inflammatory processes.

3. Diet and Lifestyle: Maintaining a balanced diet and avoiding known irritants (like spicy foods, alcohol, and caffeine) can help manage symptoms. Keeping a food diary may also help identify any triggers.

4. Medication Compliance: If prescribed medications, ensure adherence to the treatment plan. Even if symptoms improve, it’s important to follow through with the prescribed regimen to prevent recurrence.

5. Educate Yourself: Understanding the differences between acute and chronic colitis can empower you to engage in discussions with your healthcare provider about your treatment options and management strategies.


Conclusion
While your symptoms and findings are concerning, the current diagnosis leans towards acute colitis rather than ulcerative colitis. It’s essential to follow up with your healthcare provider for ongoing management and to ensure that any potential chronic conditions are monitored appropriately. If you have further questions or concerns, do not hesitate to reach out to your gastroenterologist for personalized advice and treatment options.

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