Is an HBsAg Level of 8382 Serious? Hepatitis B Risks - Gastroenterology and Hepatology

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An abnormal hepatitis B test result with a value of 8000 is considered serious?


Hello Doctor: I recently had a health check-up, and my HBsAg (EIA) for hepatitis B surface antigen came back at 8382 (+).
Does this mean I need medication? I am unsure if I am a carrier.
What does this value represent? Is it treatable? I am quite scared and have been having trouble sleeping.

Mr. He, 30~39 year old female. Ask Date: 2022/06/08

Dr. Chen Shidian reply Gastroenterology and Hepatology


They are carriers.
Medication should be considered along with viral load, liver function, and ultrasound results, and can be discussed with a gastroenterologist.

Reply Date: 2022/06/08

More Info


An HBsAg level of 8382 indicates that you are a carrier of the Hepatitis B virus (HBV). HBsAg, or Hepatitis B surface antigen, is a protein on the surface of the virus, and its presence in the blood signifies an active infection. The level of HBsAg can provide insight into the viral load and the potential for liver damage, but it is not the sole determinant for treatment decisions.

In your case, an HBsAg level of 8382 is considered high, which suggests that the virus is actively replicating in your body. This level typically warrants further evaluation, including assessing your liver function through tests such as ALT (alanine aminotransferase) and AST (aspartate aminotransferase), as well as imaging studies like an ultrasound to check for liver damage or cirrhosis.
The decision to initiate antiviral therapy is based on several factors, including:
1. Viral Load (HBV DNA): This is a direct measure of the amount of virus in your blood. High levels of HBV DNA, in conjunction with elevated liver enzymes, often indicate the need for treatment.

2. Liver Function Tests: Your ALT and AST levels provide information about liver inflammation. If these levels are significantly elevated, it may suggest active liver damage.

3. Liver Imaging: An ultrasound can help assess the liver's condition and check for signs of fibrosis or cirrhosis.

4. Symptoms: If you are experiencing symptoms such as fatigue, jaundice, or abdominal pain, these can also influence the decision to start treatment.

In terms of treatment, there are effective antiviral medications available, such as tenofovir and entecavir, which can help suppress the virus and reduce liver inflammation. The goal of treatment is to lower the viral load to undetectable levels, improve liver function, and prevent long-term complications such as cirrhosis or liver cancer.

It's important to note that while Hepatitis B can be managed effectively, it is not curable in the traditional sense. Most patients will require long-term monitoring and possibly ongoing treatment. Regular follow-ups with a healthcare provider specializing in liver diseases (hepatologist or gastroenterologist) are crucial for managing your condition.

Your anxiety about this diagnosis is understandable, but it's essential to focus on the steps you can take. Here are some recommendations:
- Consult a Specialist: Schedule an appointment with a hepatologist or a gastroenterologist who can provide a comprehensive evaluation and discuss treatment options tailored to your situation.

- Regular Monitoring: Ensure that you have regular blood tests to monitor your liver function and viral load.

- Healthy Lifestyle: Adopt a liver-friendly lifestyle by avoiding alcohol, maintaining a balanced diet, and managing stress. Regular exercise can also help improve your overall health.

- Support: Consider joining a support group for individuals with Hepatitis B. Sharing experiences with others facing similar challenges can provide emotional support and practical advice.

In summary, an HBsAg level of 8382 indicates that you are a carrier of Hepatitis B and may require treatment. It is crucial to work closely with your healthcare provider to monitor your condition and determine the best course of action. Remember that with proper management, many individuals with Hepatitis B lead healthy lives.

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