Comprehensive digestive enzymes
Dear Dr.
Su,
I have been diagnosed with autonomic nervous system dysfunction (initially diagnosed by a gastroenterologist as functional gastrointestinal disorder, later identified by a traditional Chinese medicine practitioner as stemming from autonomic nervous system dysfunction).
I am currently taking the following medications: (1) Foan 10mg, (2) Homagyl 50mg, and (3) diazepam 2mg (which I found online is a long-acting sedative with potential gastrointestinal allergic side effects).
After taking these medications for a period of time, I have experienced gastrointestinal bloating and indigestion.
I would like to ask the following:
(1) Do the aforementioned sedatives slow down gastrointestinal motility, potentially causing indigestion? (I am currently taking them once a day.)
(2) I have heard that comprehensive digestive enzymes can promote digestion.
Are there any side effects, and could they interact with the medications I am currently taking? The comprehensive digestive enzyme I am using contains the following ingredients: 1.
Biodiastase 1000 60mg, 2.
Lipase AP6 10mg, 3.
Newlase 20mg.
Thank you.
Johnson, 30~39 year old female. Ask Date: 2003/08/27
Dr. Su Baojia reply Gastroenterology and Hepatology
1.
Sedatives such as Foan and diazepam can have some degree of impact on the liver.
If liver function is abnormal, it may also lead to dyspepsia, so it is recommended that you undergo liver function tests to determine if the abnormalities are the cause.
2.
The comprehensive digestive enzymes you are taking should have minimal side effects.
However, it is advisable to consult with your physician for an evaluation before continuing their use.
Reply Date: 2003/08/27
More Info
Understanding the interaction between digestive enzymes and medications is crucial, especially for individuals experiencing gastrointestinal issues. In your case, you are currently taking Foan (likely a form of an anticholinergic), Homagyl (which may be an antibiotic or a combination medication), and Diazepam, a benzodiazepine. Let's address your concerns regarding these medications and their potential effects on digestion.
1. Impact of Diazepam on Gastrointestinal Motility: Diazepam, as a long-acting sedative, can indeed affect gastrointestinal motility. Benzodiazepines like Diazepam can lead to decreased gastrointestinal motility, which may result in symptoms such as bloating and indigestion. This is particularly relevant for individuals with functional gastrointestinal disorders, as the medication may exacerbate existing symptoms by slowing down the movement of food through the digestive tract. If you are experiencing significant bloating and digestive discomfort, it may be worth discussing with your healthcare provider whether the dosage or the necessity of Diazepam can be adjusted.
2. Digestive Enzymes and Their Interaction with Medications: The digestive enzymes you mentioned—Biodiastase, Lipase, and Newlase—are designed to aid in the breakdown of carbohydrates, fats, and proteins, respectively. Generally, these enzymes are considered safe and can help alleviate symptoms of indigestion by enhancing the digestive process. However, it is essential to note that while digestive enzymes can improve digestion, they may not directly counteract the effects of medications that slow gastrointestinal motility.
Regarding potential interactions, there is limited evidence to suggest that digestive enzymes significantly interact with benzodiazepines or other medications you are taking. However, it is always prudent to monitor how your body responds when introducing new supplements or medications. If you notice any adverse effects or worsening of your symptoms after starting the digestive enzymes, it would be wise to consult your healthcare provider.
3. Considerations for Using Digestive Enzymes: While digestive enzymes can be beneficial, they are not without potential side effects. Some individuals may experience gastrointestinal discomfort, such as cramping or diarrhea, especially if taken in excess. Additionally, if you have any underlying conditions, such as pancreatitis or other pancreatic disorders, the use of lipase supplements should be approached with caution.
4. Holistic Management of Symptoms: Given your diagnosis of autonomic nervous system dysfunction and functional gastrointestinal disorder, it may be beneficial to explore a comprehensive management plan. This could include dietary modifications, stress management techniques, and possibly alternative therapies that focus on improving gut health and motility. Engaging with a dietitian or a gastroenterologist who specializes in functional gastrointestinal disorders may provide you with tailored strategies to manage your symptoms effectively.
In conclusion, while Diazepam may contribute to slower gastrointestinal motility and digestive discomfort, the use of digestive enzymes could potentially help alleviate some of these symptoms. However, it is essential to monitor your body's response and consult with your healthcare provider for personalized advice. They can help determine the best course of action, including any necessary adjustments to your medication regimen or the introduction of digestive enzymes. Always prioritize open communication with your healthcare team to ensure safe and effective management of your health concerns.
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