Can a Patient with Severe Tricuspid Regurgitation Safely Get the COVID Vaccine? - Cardiology

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Is it safe for someone with moderate to severe tricuspid regurgitation to receive the COVID-19 vaccine?


Hello, my mother is 75 years old and has hypertension, diabetes, and hyperlipidemia, along with congenital moderate to severe tricuspid regurgitation.
She often experiences shortness of breath and difficulty breathing.
She had been taking anticoagulants for about 2 to 3 years and regularly underwent echocardiograms and blood tests at the hospital.
However, due to the pandemic, she has not taken anticoagulants or had any hospital check-ups for the past two and a half years, and she has only been taking antihypertensive medications from a local clinic.

Could you please advise if her lack of anticoagulant therapy will affect her heart? Additionally, is it safe for her to receive a vaccine? Can her heart tolerate it? Thank you for your time and assistance!

Miss Chen, 40~49 year old female. Ask Date: 2022/06/23

Dr. Li Han reply Cardiology


Hello: Based on your description, your 75-year-old mother has hypertension, diabetes, and hyperlipidemia, along with congenital moderate to severe tricuspid regurgitation symptoms.
She often experiences shortness of breath and difficulty breathing.
She has been on anticoagulants for about 2 to 3 years and regularly undergoes echocardiograms and blood tests at the hospital.
However, for the past two years, her anticoagulant therapy has been interrupted due to the pandemic, and she has only been taking medications for her three high conditions from an outpatient clinic.

Regarding your first question, the absence of anticoagulant medication can indeed impact her heart health.
Anticoagulants are considered high-risk medications, primarily used to prevent venous or cardiac thrombus formation, thereby reducing the risk of fatal pulmonary embolism or stroke.
In terms of cardiac health, if there is a history of atrial fibrillation, patients with a high stroke risk but low bleeding risk should consider anticoagulant therapy for stroke prevention.
This decision should be based on whether your mother meets the criteria for such treatment.
As for the second question, whether she can receive a vaccine, it is best to have this evaluated by her trusted physician.
A thorough assessment and discussion will help determine if vaccination is safe for her condition.

Best regards from Changhua Hospital, Ministry of Health and Welfare.

Reply Date: 2022/06/23

More Info


When considering whether a patient with severe tricuspid regurgitation can safely receive the COVID-19 vaccine, several factors must be taken into account, particularly the patient's overall health status, existing medical conditions, and the potential risks associated with vaccination.

Firstly, it is important to understand what tricuspid regurgitation is. It is a condition where the tricuspid valve, located between the right atrium and right ventricle of the heart, does not close properly, allowing blood to flow backward into the right atrium when the right ventricle contracts. This can lead to symptoms such as shortness of breath, fatigue, and swelling in the legs and abdomen. In your mother's case, her age (75 years) and the presence of comorbidities such as hypertension and possibly other cardiovascular issues increase her risk for complications from both COVID-19 and the vaccine.

Regarding her current health status, the fact that she has not taken anticoagulants for over two and a half years raises concerns. Anticoagulants are often prescribed to prevent blood clots, especially in patients with heart conditions. The absence of anticoagulation therapy could potentially lead to an increased risk of thromboembolic events, which could complicate her existing heart condition. It is crucial that she undergoes a thorough evaluation by her healthcare provider to assess her current cardiovascular status and determine whether she should resume anticoagulation therapy.

Now, concerning the COVID-19 vaccine, the Centers for Disease Control and Prevention (CDC) and other health organizations recommend vaccination for individuals with underlying health conditions, including those with heart disease. The benefits of vaccination, which include a significant reduction in the risk of severe illness, hospitalization, and death from COVID-19, generally outweigh the potential risks associated with the vaccine.
For patients with severe tricuspid regurgitation, the vaccine can be administered, but it is essential to monitor for any adverse reactions, especially given her age and existing health conditions. It is advisable for her to receive the vaccine in a controlled environment, such as a healthcare facility, where she can be monitored for any immediate side effects.
Additionally, it is important to consult with her cardiologist or primary care physician before vaccination. They can provide personalized advice based on her specific health status, including whether any adjustments to her medications or additional monitoring are necessary.
In summary, while your mother can likely receive the COVID-19 vaccine, it is crucial to ensure that her overall health is stable and that she is under appropriate medical supervision. Resuming anticoagulation therapy may also be necessary, depending on her current cardiovascular assessment. The decision should be made collaboratively with her healthcare team to ensure her safety and well-being.

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