the Side Effects of You-Ru in Treating Uterine Fibroids

Taking You-Ru?

Hello Doctor: I have uterine fibroids (one measuring 0.5 cm and another 2 cm).
I started taking Yao Ru in early April, but not only did I not stop menstruating, my menstrual cycle has decreased to less than 20 days since May (it was previously around 26 days and stable).
My period has also extended to about 10 days, and the pain continues until the end of my cycle.
The bleeding has increased, and the blood clots are larger than before.
I experience menstrual pain for about half of the month, which severely affects my life.
I initially hoped that taking Yao Ru would stop my menstruation and help control the fibroids, but it seems to have only disrupted my menstrual cycle.
I'm considering directly undergoing hysteroscopic surgery to remove the fibroids.
😭 I would like to ask if this is a common side effect of Yao Ru, or am I an exception? Given this situation, should I continue taking the medication or would you recommend surgery instead?

Ni Ni, 20~29 year old female. Ask Date: 2022/06/29

Dr. Cao Guotao reply Obstetrics and Gynecology

Hello, it is recommended to consider alternative treatment methods.
Wishing you good health.

Reply Date: 2022/06/29

More Info

Dear patient,
Thank you for reaching out with your concerns regarding the use of You-Ru (Ulipristal Acetate) for treating uterine fibroids. I understand that you have been experiencing significant changes in your menstrual cycle and increased discomfort since starting the medication. Let’s break down your concerns and provide some clarity on the situation.

Understanding You-Ru and Its Side Effects
You-Ru is a medication often prescribed to manage symptoms associated with uterine fibroids, particularly to help reduce heavy menstrual bleeding and to potentially shrink fibroids. However, like any medication, it can have side effects, and individual responses can vary significantly.

1. Menstrual Changes: It is not uncommon for patients taking You-Ru to experience changes in their menstrual cycle. This can include alterations in cycle length, duration of bleeding, and the volume of menstrual flow. Some patients report shorter cycles, while others may experience prolonged bleeding or heavier periods. The symptoms you describe—shortened cycles, prolonged bleeding, and increased menstrual pain—are indeed documented side effects of this medication.

2. Pain and Discomfort: The increased menstrual pain you are experiencing could be attributed to the hormonal changes induced by You-Ru. This medication works by modulating the effects of progesterone, which can lead to changes in the uterine lining and may cause increased cramping and discomfort during menstruation.

3. Blood Clots: The presence of larger blood clots during menstruation can also be a side effect of hormonal treatments. As the uterine lining changes, the nature of menstrual bleeding can alter, leading to the expulsion of larger clots.

Should You Continue the Medication?
Given your symptoms and the significant impact they are having on your quality of life, it is essential to weigh the benefits of continuing You-Ru against the side effects you are experiencing. Here are some considerations:
- Consult Your Healthcare Provider: It is crucial to discuss your symptoms with your healthcare provider. They can assess whether these side effects are typical for you or if they indicate a need to adjust your treatment plan. They may suggest monitoring your symptoms for a short period or consider alternative therapies.

- Surgical Options: If the medication is not providing the relief you were hoping for and your quality of life is severely affected, discussing surgical options, such as a hysteroscopic myomectomy (removal of fibroids), may be warranted. This procedure can directly address the fibroids and potentially alleviate the symptoms you are experiencing.

- Alternative Treatments: There are other medical treatments available for managing uterine fibroids, including hormonal therapies, GnRH agonists, or even non-hormonal options. Your healthcare provider can help you explore these alternatives based on your specific situation and preferences.

Conclusion
In summary, the side effects you are experiencing with You-Ru are not uncommon, but they are significant enough to warrant a discussion with your healthcare provider. It is essential to have an open dialogue about your symptoms, treatment goals, and any concerns you may have regarding your current medication. Your well-being is the priority, and there are multiple pathways to manage your condition effectively.

Please do not hesitate to reach out to your healthcare provider for further evaluation and to discuss the best course of action for your situation. Your health and comfort are paramount, and there are solutions available to help you regain control over your menstrual health and overall quality of life.

Best wishes for your health and well-being.

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