Impact of Male Medication Use on Pregnancy Outcomes: What You Need to Know - Obstetrics and Gynecology

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The impact of medication use in men on pregnancy outcomes?


Hello Doctor: I am a male and I would like to inquire about a concern.
I have been experiencing stomach discomfort for the past few months and sought medical attention.
From March to the end of May, I was prescribed "Moshu Weiqing Tablets 5mg" (three times a day) and "Dexilant 60mg Extended-Release Capsules" (once a day).
After May 31, I switched to "Desonate Film-Coated Tablets 100mg" (three times a day) and continued with "Dexilant 60mg Extended-Release Capsules" (once a day).
However, during the course of my medication, my wife became pregnant around the first and second week of June.
I am concerned whether this will have any impact on the fetus.
I hope Dr.
Zhang can provide some clarification.
Thank you very much.

Mr. Wang, 30~39 year old female. Ask Date: 2022/07/05

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, based on the situation you described, is there an impact probability? Thank you! Wishing you peace and health.
Dr.
Zhang

Reply Date: 2022/07/05

More Info


When it comes to the impact of male medication use on pregnancy outcomes, it is essential to understand that while the primary focus is often on the medications taken by the pregnant individual, the medications taken by the male partner can also play a role in reproductive health and fetal development.

In your case, you mentioned using medications such as "摩舒胃清錠" (Moshu Weiqing Tablet) and "得喜胃通" (Deshi Weitong) for gastrointestinal discomfort, followed by "得舒特膜衣錠" (Deshut Membrane-Coated Tablet) and continuing with "得喜胃通." It is important to note that the medications you have taken are primarily aimed at treating gastrointestinal issues, and their potential effects on sperm quality and fertility are generally less concerning than those of other classes of medications, such as certain antidepressants, anti-anxiety medications, or chemotherapy agents.

Research indicates that some medications can affect sperm quality, motility, and morphology, which could potentially impact fertility. However, the medications you mentioned are not typically associated with significant adverse effects on sperm or fetal development. For instance, proton pump inhibitors (PPIs) and H2 receptor antagonists, which are often used for gastric issues, have not been shown to have a detrimental effect on male fertility or pregnancy outcomes.

The timing of your medication use is also crucial. Since your wife became pregnant in early June, and you were taking these medications prior to that, it is unlikely that they would have had a direct impact on the embryo during the very early stages of development. The first few weeks of pregnancy are critical for fetal development, but the embryo is primarily influenced by the maternal environment and any medications she may be taking.

It is also worth noting that the FDA categorizes medications based on their safety during pregnancy. While the specific medications you mentioned may not have extensive studies regarding their effects on pregnancy outcomes, they are generally considered safe for use in males without significant concerns for fetal health. However, it is always best to consult with a healthcare provider regarding any specific concerns about medication use and its potential impact on fertility and pregnancy.

In summary, while it is wise to be cautious about medication use when planning for a family, the medications you have taken for gastrointestinal issues are unlikely to have a significant impact on your wife's pregnancy or the health of your future child. It is always advisable to discuss any concerns with your healthcare provider, who can provide personalized guidance based on your medical history and the specific medications involved. Regular prenatal care and open communication with your partner's healthcare provider will also help ensure a healthy pregnancy.

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