Do You Need to Stop Medications Before Carbon-13 Breath Test? - Gastroenterology and Hepatology

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Is it necessary to stop medication before the carbon-13 breath test for Famotidine 20 mg and Hyoscine Butylbromide 40 mg?


Before undergoing a carbon-13 breath test, is it necessary to discontinue the medications Famotidine 20 mg and Otilonium 40 mg a few weeks prior? Thank you!

Xiao Fei, 30~39 year old female. Ask Date: 2022/07/15

Dr. Yang Zhichao reply Gastroenterology and Hepatology


Hello Mr.
Hsiao-Fei, there is no need to intentionally stop your medication.
Please follow your hospital's guidelines to complete the examination.
Thank you for your inquiry.

Reply Date: 2022/07/15

More Info


When preparing for a Carbon-13 breath test, it is essential to consider the medications you are currently taking, as certain drugs can potentially interfere with the accuracy of the test results. The Carbon-13 breath test is primarily used to assess conditions such as Helicobacter pylori infection or to evaluate carbohydrate malabsorption, such as in cases of lactose intolerance or fructose malabsorption.

Medications and Their Impact:
1. Famotidine (法瑪鎮膜衣錠): This medication is an H2 receptor antagonist commonly used to reduce stomach acid production. It can potentially affect the results of breath tests by altering gastric pH and, consequently, the metabolism of the test substrate. Therefore, it is generally recommended to discontinue famotidine at least 24 hours before the test to avoid any interference.

2. Otilonium Bromide (Otilonium腸痙平膜衣錠): This medication is an antispasmodic used to relieve gastrointestinal spasms. While it is less likely to directly interfere with the breath test, it is still advisable to consult your healthcare provider regarding its use prior to testing. The rationale is that any medication affecting gastrointestinal motility could potentially influence the results.

General Recommendations:
- It is crucial to inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements. They can provide specific guidance on whether you should stop these medications and for how long before the test.

- Typically, it is advisable to stop medications that can alter gastric pH or motility at least 24 hours prior to the Carbon-13 breath test. However, the exact duration may vary based on individual circumstances and the specific medication.

- Always follow your healthcare provider's instructions regarding medication management before the test. If you have concerns about stopping your medications, discuss them with your doctor to weigh the risks and benefits.

Conclusion:
In summary, for the Carbon-13 breath test, it is generally recommended to stop taking famotidine at least 24 hours prior to the test. For otilonium, consult your healthcare provider for specific advice. Proper preparation is key to obtaining accurate test results, which will ultimately guide your diagnosis and treatment plan. Always prioritize open communication with your healthcare provider regarding any changes to your medication regimen.

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