the Impact of Emergency Contraceptive Pills on Pregnancy Outcomes - Obstetrics and Gynecology

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Emergency contraceptive pill


Hello, my wife purchased emergency contraceptive pills (specifically, two doses of EllaOne) from the pharmacy, along with one anti-nausea pill.
She took the first dose on the evening of August 9, after our encounter on August 8, and then took another dose 12 hours later on the morning of August 10, continuing this pattern for a total of three doses.
Her menstrual period was expected to start on August 21 (the previous month it started on July 21), but the contraception failed.
We have since visited an obstetrician-gynecologist and confirmed that she is eight weeks pregnant.

After consulting with at least five obstetricians, we have received mixed opinions regarding the health of the fetus.
Two doctors suggested that the medication could potentially cause fetal malformations, female reproductive organ cancers, and other complications, recommending termination of the pregnancy.
However, one doctor expressed a more cautious view, stating that while the timing of the medication may coincide with ovulation, the fertilized egg has not yet implanted, and therefore the medication should not have affected it.
Due to our lack of understanding regarding the pharmacological effects of the medication, we are very concerned about any potential impact on the baby.
Please help us understand the extent of the effects this medication may have on the fetus.
Thank you.

LL, 30~39 year old female. Ask Date: 2003/09/17

Dr. Huang Jianxun reply Obstetrics and Gynecology


Hello: Emergency contraceptive pills contain high doses of hormones.
Please read the accompanying leaflet, as it should outline the potential effects you mentioned.
However, it is also reasonable to consider the perspective retained by another obstetrician you referenced.
As for how it will affect you, doctors are not omniscient; they can only provide explanations based on pharmacology and physiology.
The decision on how to proceed ultimately lies with you.
This is just a personal opinion for your reference.

Reply Date: 2003/09/17

More Info


Emergency contraceptive pills (ECPs), such as the one you mentioned (Levonorgestrel), are designed to prevent pregnancy after unprotected intercourse. They are most effective when taken as soon as possible after the event, ideally within 72 hours, but can be taken up to 120 hours post-intercourse. The concern regarding their impact on an existing pregnancy is a common one, especially when there is uncertainty about the timing of ovulation and fertilization.

First, it's important to clarify how ECPs work. They primarily function by delaying or inhibiting ovulation, preventing fertilization, or preventing a fertilized egg from implanting in the uterus. If a woman is already pregnant at the time of taking ECPs, the medication is not effective in terminating the pregnancy. Current research indicates that ECPs do not pose a risk of causing birth defects or other adverse effects on a developing fetus if taken after conception has already occurred.

In your case, since you mentioned that your wife is already eight weeks pregnant, it is crucial to understand that the ECPs would not have affected the pregnancy once implantation has taken place. The consensus among medical professionals is that ECPs do not have teratogenic effects (causing malformations) on an established pregnancy. The concern raised by some healthcare providers regarding potential risks, such as congenital anomalies or cancers, is largely unfounded in the context of ECP use during an existing pregnancy.

The FDA categorizes medications based on their safety during pregnancy. Levonorgestrel, the active ingredient in many ECPs, is classified as Category X when used for abortion purposes, but it is not classified as harmful when taken before a pregnancy is established. The risk of birth defects or other complications from taking ECPs after conception is considered negligible.

It is understandable to feel anxious about the health of your unborn child, especially when conflicting opinions arise from different healthcare providers. However, the prevailing medical opinion is that ECPs do not harm an existing pregnancy. The best course of action is to continue regular prenatal care, including ultrasounds and check-ups, to monitor the health and development of the fetus.

If there are any specific concerns about the pregnancy or if any unusual symptoms arise, it is essential to communicate openly with your obstetrician. They can provide personalized advice based on your wife's medical history and the specifics of her pregnancy.

In summary, while it is natural to worry about the effects of medications taken during early pregnancy, the evidence suggests that ECPs do not adversely affect fetal development when taken after conception. It is crucial to maintain a positive outlook and focus on prenatal care to ensure the best possible outcome for your baby.

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