Consultation on Antiarrhythmic Medications
Hello Director: Currently, due to arrhythmia, premature atrial contractions, and paroxysmal atrial fibrillation, I have been taking one tablet of Rynol (Ranolazine) twice daily for over two months.
My heart rate was over 100 beats per minute before taking the medication, and it has decreased to over 90 beats per minute after taking it.
The discomfort from arrhythmia, characterized by irregular heartbeats that fluctuate between fast and slow, has reduced to about 1-2 times a week, but I still experience palpitations and missed beats.
Is the current use of Rynol considered effective in controlling my condition? Additionally, the doctor arranged for a myocardial perfusion scan, which showed mild stenosis of the right coronary artery at 10-15%.
My most recent blood test results were: HDL 35, LDL 120, and ALT 60.
The doctor mentioned the risk of myocardial infarction, so he prescribed 2 mg of Lisinopril and 81 mg of Enteric-coated Aspirin.
I would like to ask if it is necessary to take these two medications at this stage? Given that my ALT is already at 60, could Lisinopril further elevate the ALT levels? Should I start taking them immediately, or can I monitor my condition and decide later? Thank you for your response, Director.
Liu Xiansheng, 60~69 year old female. Ask Date: 2022/07/27
Dr. He Dongjin reply Cardiology
Hello, reducing to 1-2 times a week is considered controlled, unless the medication dosage is increased.
With an ALT of 60 and LDL of 120, if you have concerns about liver side effects, you can start with dietary control and reduce oil intake.
We can discuss further after your blood test results.
Changhua Hospital cares about you.
Reply Date: 2022/07/27
More Info
Managing atrial fibrillation (AF) and associated conditions can be complex and requires careful consideration of medication, lifestyle changes, and ongoing monitoring. Based on your description, it appears that you have been prescribed a regimen that includes a beta-blocker (likely the "律諾膜衣錠" you mentioned, which is probably a brand name for a beta-blocker) to manage your heart rate and rhythm.
Effectiveness of Current Medication
From your report, it seems that the beta-blocker has had a positive effect on your heart rate, reducing it from over 100 beats per minute to around 90 beats per minute after medication. This is a good sign, as effective management of AF often involves controlling the heart rate to prevent complications such as heart failure or stroke. The fact that your episodes of irregular heartbeats have decreased to 1-2 times a week suggests that the medication is helping to stabilize your condition.
However, you also mention experiencing palpitations and irregular heartbeats, which can be distressing. It's important to communicate these symptoms to your healthcare provider, as they may indicate that your current dosage needs adjustment or that additional therapies may be necessary.
Additional Medications and Concerns
Regarding the new medications prescribed—力清 (likely a statin) and 諾比林 (likely aspirin)—these are often used in patients with cardiovascular risks, especially when there is evidence of coronary artery disease, as indicated by your myocardial perfusion scan showing mild narrowing of the right coronary artery.
1. 力清 (Statin): Statins are used to lower LDL cholesterol levels and can help reduce the risk of cardiovascular events, such as heart attacks. Given your LDL level of 120 mg/dL, which is above the optimal range, starting a statin may be appropriate to manage your cholesterol levels and reduce your cardiovascular risk.
2. 諾比林 (Aspirin): Aspirin is often prescribed for its antiplatelet effects, particularly in patients with a history of heart disease or those at risk of heart attacks. Given your history of atrial fibrillation and the findings from your myocardial perfusion scan, aspirin may help prevent clot formation, which is a risk in AF patients.
Concerns About ALT Levels
You mentioned that your ALT level is elevated at 60. While statins can sometimes cause liver enzyme elevations, the increase is usually mild and reversible. It is essential to monitor liver function tests periodically after starting a statin. If your ALT levels rise significantly or if you experience symptoms such as jaundice or severe fatigue, your healthcare provider may need to reassess your medication regimen.
Recommendations
1. Continue Monitoring: Keep track of your symptoms, heart rate, and any side effects from medications. Regular follow-ups with your healthcare provider are crucial to ensure that your treatment plan is effective and safe.
2. Discuss Concerns: Bring up your concerns about the new medications and your ALT levels with your healthcare provider. They can provide personalized advice based on your overall health status and may suggest alternative treatments if necessary.
3. Lifestyle Modifications: In addition to medication, consider lifestyle changes that can help manage AF and improve heart health. This includes maintaining a healthy diet, engaging in regular physical activity, managing stress, and avoiding stimulants that can exacerbate heart rhythm issues.
4. Follow-Up Testing: Ensure that you have follow-up blood tests scheduled to monitor your cholesterol levels and liver function, as well as any additional cardiac evaluations as recommended by your physician.
In summary, while your current medication appears to be effective in managing your heart rate and rhythm, ongoing communication with your healthcare provider is essential to address any concerns and optimize your treatment plan.
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