Accidental Ingestion of Cholesterol Medication by Toddler: What to Know - Pediatrics

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A two-and-a-half-year-old child accidentally ingested clobetasol?


Currently, I am taking a lipid-lowering medication called "Crestor." I accidentally dropped a pill on the sofa and didn't think much of it when I couldn't find it at the time.
Today, my child was playing on the sofa and found that pill, putting it in their mouth.
By the time I noticed, a significant portion had already dissolved in their mouth.
I immediately took my child to rinse their mouth, but I'm not sure if they actually swallowed any (they probably did).
Doctor, what effects could occur from a two-and-a-half-year-old child accidentally ingesting a Crestor pill?

Ye Hsien-Yu, 30~39 year old female. Ask Date: 2022/07/29

Dr. Xiao Kaiwen reply Pediatrics


The main function of Rosuvastatin is to lower cholesterol and triglycerides.
After administration, it is metabolized by the kidneys.
Rare side effects include myositis, myalgia, and liver function abnormalities.
Therefore, in the case of accidental overdose of Rosuvastatin in young children, it would be advisable to conduct tests related to cholesterol, triglycerides, liver and kidney function, and muscle enzymes.

Reply Date: 2022/07/29

More Info


Accidental ingestion of medication by toddlers is a common concern for parents, and it is crucial to understand the potential effects and necessary actions to take in such situations. In this case, the medication in question is "冠脂妥" (Rosuvastatin), which is a statin used to lower cholesterol levels.
First and foremost, it is essential to assess the amount ingested. Since the child is two and a half years old, even a small amount of medication can potentially lead to adverse effects. Statins like Rosuvastatin are generally well-tolerated in adults, but the effects on young children are not as well-studied.

Potential Effects of Rosuvastatin on Toddlers
1. Gastrointestinal Distress: The most common side effects of statins in adults include gastrointestinal issues such as nausea, vomiting, and diarrhea. In toddlers, these symptoms may manifest similarly, and the child may experience discomfort or an upset stomach.

2. Muscle Pain or Weakness: Although rare, statins can cause muscle-related side effects, including myopathy or rhabdomyolysis. In children, this is less common, but if the child exhibits unusual weakness or pain, it should be reported to a healthcare provider immediately.

3. Liver Function: Statins can affect liver enzymes, and while this is more of a concern in adults, it is still important to monitor liver function in children who have ingested statins. Symptoms of liver issues can include jaundice (yellowing of the skin or eyes), dark urine, or abdominal pain.

4. Allergic Reactions: Although rare, any medication can cause an allergic reaction. Signs of an allergic reaction include rash, itching, swelling, or difficulty breathing. If any of these symptoms occur, seek emergency medical attention.


Immediate Actions to Take
1. Contact Poison Control: The first step after an accidental ingestion is to contact your local poison control center. They can provide specific guidance based on the amount ingested and the child's weight.

2. Monitor the Child: Keep a close eye on the child for any signs of distress or unusual behavior. If the child shows any concerning symptoms, such as vomiting, lethargy, or difficulty breathing, seek medical attention immediately.

3. Do Not Induce Vomiting: Unless instructed by a medical professional, do not attempt to induce vomiting, as this can lead to further complications.

4. Follow-Up with a Healthcare Provider: Regardless of whether the child shows symptoms, it is advisable to follow up with a pediatrician or healthcare provider to discuss the incident and any necessary monitoring or tests.


Prevention Tips
To prevent future incidents, consider the following:
- Medication Storage: Always store medications out of reach of children, preferably in a locked cabinet.

- Education: Teach older children about the dangers of medications and the importance of not touching or consuming them without adult supervision.

- Regular Checks: Regularly check your living space for any dropped medications or pills that may be within reach of curious toddlers.

In conclusion, while the accidental ingestion of Rosuvastatin by a toddler can be concerning, prompt action and monitoring can help mitigate potential risks. Always consult with healthcare professionals for personalized advice and care.

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