Why Does One Side of the Face Sweat While the Other Doesn't? - Neurology

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Hemifacial anhidrosis?


Hello Dr.
Yeh: My mother is 51 years old.
Recently, she has noticed that her face becomes red and sweats on the right side when exposed to hot weather or during intense exercise, while the left side does not sweat at all.
What could be the reason for this phenomenon of sweating only on one side? I would appreciate your explanation, Dr.
Yeh.

Mr. Huang, 20~29 year old female. Ask Date: 2003/09/20

Dr. Ye Boshou reply Neurology


Hello Mr.
Huang: The side of your mother's face that does not sweat may indicate a lesion in the sympathetic nervous system.
Further examination is necessary, and she should schedule an appointment with a neurology clinic.

Reply Date: 2003/09/20

More Info


The phenomenon of one side of the face sweating while the other does not can be attributed to several underlying factors, primarily involving the autonomic nervous system, particularly the sympathetic and parasympathetic branches. In your mother's case, the asymmetrical sweating response could indicate a disruption or dysfunction in the autonomic pathways that control sweat gland activity.

When the body is exposed to heat or engages in vigorous physical activity, the hypothalamus, which regulates body temperature, signals the sweat glands to produce sweat to cool the body down. This process is mediated by the sympathetic nervous system, which activates sweat glands through the release of neurotransmitters like acetylcholine. If there is a blockage or dysfunction in the nerve pathways that innervate the sweat glands on one side of the face, it can lead to the observed phenomenon where one side sweats while the other remains dry.

In your mother's case, the lack of sweating on the left side of her face could be indicative of a condition known as "Horner's syndrome," which is characterized by a disruption of sympathetic nerve pathways. This syndrome can result from various causes, including trauma, tumors, or vascular issues affecting the sympathetic nerves. Another possibility is a condition called "Frey's syndrome," which can occur after facial nerve injury, leading to sweating in the area of the cheek when eating or in response to heat, while the opposite side may not sweat at all.

Additionally, it is essential to consider other factors that might contribute to this asymmetrical sweating. For example, certain medications can affect sweat production, and hormonal changes, especially during menopause, can also influence the autonomic nervous system's function. Given that your mother is 51 years old, she may be experiencing hormonal fluctuations associated with menopause, which can impact various bodily functions, including sweating.

To further investigate this issue, it would be prudent for your mother to consult with a neurologist or a specialist in autonomic disorders. They may recommend diagnostic tests, such as a sympathetic skin response test or a sweat test, to evaluate the function of the sweat glands and the underlying nerve pathways. Imaging studies, like MRI or CT scans, may also be necessary to rule out any structural abnormalities that could be affecting the nerves.

In summary, the asymmetrical sweating observed in your mother could be due to a variety of factors, including nerve dysfunction, hormonal changes, or other underlying medical conditions. A thorough evaluation by a medical professional is essential to determine the exact cause and to develop an appropriate treatment plan. In the meantime, ensuring that your mother stays hydrated and cool during hot weather or physical activity can help manage her symptoms.

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