Managing Adenomyosis: Treatment Options and Menstrual Cycle Concerns - Obstetrics and Gynecology

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Adenomyosis


I have been diagnosed with adenomyosis for two years, and I didn't take it seriously until this year when I started getting vaccinated.
After being diagnosed, my menstrual cycle became irregular.
I didn't have my period from January to February, had it for half a month in March, didn't have it in April, tested positive for COVID-19 on May 7, and had my period from May 1 until July for almost three months.
In mid-July, I went for a consultation and underwent a minor procedure to remove endometrial blood clots.
The doctor did not believe my body needed rest and said I could return to work.
However, I vomited everything I ate or drank and felt completely weak.
The next day, I went to work, but due to excessive blood loss, I became very weak and had to go to the emergency room for a blood transfusion, as my hemoglobin dropped to 5.
The next day, I switched hospitals for treatment, rested for a week, and was prescribed hemostatic agents and progesterone for half a month.
Can I still take progesterone during my menstrual period?

An Baobei, 30~39 year old female. Ask Date: 2022/08/06

Dr. Lin Xinwang reply Obstetrics and Gynecology


Hello: If menstruation occurs, you can stop the medication and observe.
If there is abnormal bleeding, you should see a doctor to determine the issue.
Adenomyosis can lead to heavy menstrual bleeding, dysmenorrhea, and lower abdominal pain without causing anemia.
It is recommended to take estrogen (E) and progesterone (P) during the first week after menstruation, and then take progesterone from day 14 to day 21.
After stopping the medication, monitor the menstrual situation; this can help regulate for three months.
If the condition does not improve, the last option would be surgical treatment.

Reply Date: 2022/08/06

More Info


Managing adenomyosis can be quite challenging, especially when it comes to the symptoms associated with menstrual irregularities and the overall impact on your quality of life. Adenomyosis is a condition where the endometrial tissue, which normally lines the uterus, grows into the muscular wall of the uterus. This can lead to heavy menstrual bleeding, severe cramps, and other complications.

From your description, it seems that you have been experiencing significant menstrual irregularities and complications, including prolonged bleeding and severe fatigue due to blood loss. It's crucial to address these symptoms effectively to improve your overall health and well-being.


Treatment Options for Adenomyosis
1. Hormonal Therapy: Hormonal treatments are often the first line of defense for managing adenomyosis. Medications such as hormonal birth control pills, patches, or intrauterine devices (IUDs) can help regulate your menstrual cycle and reduce heavy bleeding. Progestins, such as medroxyprogesterone acetate, can also be effective in managing symptoms.

2. GnRH Agonists: Gonadotropin-releasing hormone (GnRH) agonists can help reduce estrogen levels, leading to a decrease in the size of adenomyosis and alleviating symptoms. However, these medications are typically used for a limited time due to potential side effects, including bone density loss.

3. Non-Hormonal Medications: Non-steroidal anti-inflammatory drugs (NSAIDs) can help manage pain associated with adenomyosis. However, they do not address the underlying condition.

4. Surgical Options: In cases where conservative treatments are ineffective, surgical options may be considered. This can include procedures to remove adenomyosis or, in severe cases, a hysterectomy (removal of the uterus). It's important to discuss the risks and benefits of surgery with your healthcare provider.


Menstrual Cycle Concerns and Use of Progesterone
Regarding your question about taking progesterone (黄体素) during your menstrual cycle, it is essential to consult your healthcare provider. Progesterone can help regulate your menstrual cycle and reduce heavy bleeding, but its use should be tailored to your specific situation. If you are currently experiencing heavy bleeding, your doctor may recommend delaying the use of progesterone until your bleeding is more controlled.


Managing Symptoms and Overall Health
Given your recent experiences with severe fatigue and blood loss, it's crucial to prioritize your health. Here are some recommendations:
- Monitor Your Symptoms: Keep a detailed record of your menstrual cycle, including the duration and heaviness of your bleeding, as well as any associated symptoms like pain or fatigue. This information can help your healthcare provider make informed decisions about your treatment.

- Nutritional Support: Focus on a balanced diet rich in iron and other nutrients to help combat fatigue from blood loss. Foods such as leafy greens, lean meats, beans, and fortified cereals can be beneficial.

- Hydration: Ensure you are staying well-hydrated, especially if you are experiencing vomiting or gastrointestinal distress. Electrolyte solutions may also help if you are losing fluids.

- Follow-Up Care: Regular follow-up appointments with your healthcare provider are essential to monitor your condition and adjust treatment as necessary. If you experience any new or worsening symptoms, seek medical attention promptly.

In conclusion, managing adenomyosis requires a comprehensive approach that includes hormonal therapy, symptom management, and possibly surgical intervention. Always consult with your healthcare provider before making any changes to your treatment plan, especially regarding the use of progesterone during your menstrual cycle. Your health and well-being should always be the priority, and your provider can help guide you through the best options for your specific situation.

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