Lymph Node Issues: Could It Be Lymphoma? - Oncology

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When it comes to lymph nodes, especially those that are enlarged or painful, it is natural to have concerns about potential underlying conditions, including lymphoma. Based on your description, it seems you have been experiencing a swollen lymph node in the submandibular region (under the jaw) for several months. You have sought medical advice from two different clinics, both of which prescribed antibiotics and indicated that the lymph node was likely reactive rather than malignant.
Lymph nodes can become enlarged for various reasons, including infections, inflammation, and malignancies. In your case, the fact that the lymph node has decreased in size significantly (by about two-thirds) after antibiotic treatment is a positive sign. This suggests that the enlargement may have been due to a reactive process, such as an infection, rather than a malignancy like lymphoma.
Lymphoma typically presents with persistent lymphadenopathy (swollen lymph nodes) that does not resolve over time, often accompanied by other systemic symptoms such as unexplained weight loss, night sweats, and fever. The fact that your lymph node has decreased in size and is no longer painful after treatment is reassuring. Additionally, the fluctuation in size you describe—where the lymph node feels larger after prolonged touching and smaller after a period of not touching—can be attributed to the lymphatic system's response to pressure and inflammation rather than a sign of malignancy.

It is also worth noting that lymph nodes can remain palpable even after they have decreased in size, especially if they were previously enlarged. This does not necessarily indicate a serious problem. The normal findings from your nasopharyngoscopy further support the idea that there is no significant underlying pathology in the head and neck region.

However, it is essential to continue monitoring the lymph node. If it begins to enlarge again, becomes painful, or if you develop new symptoms, it would be prudent to seek further evaluation. This could include imaging studies such as an ultrasound or CT scan, and possibly a biopsy if there is any concern about malignancy.
In summary, while your concerns about lymphoma are understandable, the clinical picture you have described—especially the reduction in size and lack of pain—suggests that the lymph node is likely reactive rather than malignant. It is always best to maintain open communication with your healthcare provider and follow their recommendations for monitoring your condition. If you feel uncertain or anxious about your symptoms, do not hesitate to seek a second opinion or further evaluation to ensure peace of mind.